Synthesis of Cularine Type Compounds (Studies on the Syntheses of Heterocyclic Compounds. CCXXXVI)
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概要
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1-(4-Hydroxy-3-methoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-ol (V) was oxidized with potassium ferricyanide to dienone (VI), which was subjected to dienone-phenol rearrangement with hydrochloric acid in acetic acid to give the cularine type compound (XXI). These reactions provide a possible model for biogenesis of cularine and related alkaloids. Moreover, this paper described the preparation of V.
- 公益社団法人日本薬学会の論文
- 1968-06-25
著者
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亀谷 哲治
Pharmaceutical Institute, Tohoku University School of Medicine
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福本 圭一郎
東北大・薬
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福本 圭一郎
Pharmaceutical Institute, Tohoku University
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菊地 豊彦
東京薬科大学
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亀谷 哲治
Pharmaceutical Institute Medical Faculty University Of Osaka
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福本 圭一郎
Pharmaceutical Institute Tohoku University School Of Medicine
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菊地 豊彦
Pharmaceutical Institute, Tohoku University School of Medicine
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