Studies on the Syntheses of Heterocyclic Compounds. DCLXXI. An Alternative Total Synthesis of Yohimbine

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概要

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• Birch reduction of 16-carboxy-15,16,17,18,19,20-hexadehydro-17-methoxyyohimbane (XII), followed by esterification with diazomethane, gave 15,17,18,20-tetradehydro-17-meth-oxy-16-methoxycarbonylyohimbane (XIII), which was converted into 15,16-dehydroyohimbinone (II). This was correlated with yohimbine (IV) by the present authors.

• 公益社団法人日本薬学会の論文
• 1976-10-25

著者

• 亀谷 哲治

  Pharmaceutical Institute, Tohoku University School of Medicine

• 平井 美朗

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 福本 圭一郎

  東北大・薬

• 平井 美朗

  Pharmaceutical Institute, Tohoku University

• 福本 圭一郎

  Pharmaceutical Institute, Tohoku University

• 平井 美朗

  Pharmaceutical Institute Tohoku University

• 亀谷 哲治

  Pharmaceutical Institute Medical Faculty University Of Osaka

• 福本 圭一郎

  Pharmaceutical Institute Tohoku University School Of Medicine

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