TOTAL SYNTHESIS OF (+)-MONOMORINE I VIA ASYMMETRIC α-KETONIC CLEAVAGE OF 8-AZABICYCLO[3.2.1]OCTAN-3-ONE

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概要

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• The total synthesis of (+)-monomorine I and preparation of cis-2,5-difunctionalized pyrrolidines, as a chiral synthon, starting with asymmetric cleavage of the 'fork head' ketone of 8-azabicyclo[3.2.1]octan-3-one are described.

• 社団法人日本薬学会の論文
• 1990-07-25

著者

• 平井 美朗

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 百瀬 雄章

  Faculty of Pharmaceutical Sciences, Kinki University

• 百瀬 雄章

  富山医科薬科大学薬学部

• 豊岡 尚樹

  Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutical University

• 関 澄江

  Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutical University

• 関 澄江

  Research Institute Fuji Chemical Industries Ltd.

• 平井 美朗

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 百瀬 雄章

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 豊岡 尚樹

  富山大学薬学部薬品製造学研究室

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