Studies on Coenzyme Analogs. I. Synthesis of 3-β-D-Ribofuranosyl-2-oxo-2,3-dihydropyrimidine (6-Deoxyuridine) and its 5'-Phosphate.
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A new nucleoside, 3-(β-D-ribofuranosyl)-2-oxo-2,3-dihydropyrimidine (6-deoxyruidine), was synthesized from 2-hydroxypyrimidin-1-ylmercury chloride and 2,3,5-tri-O-benzoyl-ribofuranosyl chloride, followed by removal of protecting groups. 6-Deoxyruidine 5'-monophosphate and 2'(or 3'), 5'-diphosphate were obtained by phosphorylation of 6-deoxyuridine.
- 公益社団法人日本薬学会の論文
- 1960-04-25
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