Effect of Lactobacillus rhamnosus KY-3 and Cellobiose as Synbiotics on Lipid Metabolism in Rats

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概要

• 論文の詳細を見る

• Lactobacillus rhamnosus KY-3 is a fermentative bacterium that is used for the industrial production of L-lactic acid We have examined the effect of L rhamnosus KY-3 and cellobiose as synbiotics on lipid metabolism in rats Rats were fed on a 20% casein diet (C) supplemented with either 1 7% L rhamnosus KY-3 (KY-3), 10% cellobiose (CEB), or 1 7% L rhamnosus KY-3 and 10% cellobiose (KY-3 + CEB) for 13d The concentrations of serum total lipids, triacylglycerol, total cholesterol, and phospholipids were significantly reduced in rats fed a KY-3+CEB diet in comparison to those on the C, KY-3 and CEB diets There was an increase in the weight of cecal contents and a significant increase in the amount of cecal short-chain fatty acids (SCFA) The dry weight of excretion increased additively upon the simultaneous administration of L rhamnosus KY-3 and cellobiose (KY-3 + CEB) The amount of excreted fecal bile acids did not differ among the groups in this study These findings support the hypothesis that the promotion of cecal fermentation can lower the level of serum lipids These results suggest that simultaneous administration of L rhamnosus KY-3 and cellobiose as synbiotics has a beneficial effect on lipid metabolism

• 日本ビタミン学会の論文

著者

• Sakai Kenji

  Department of Plant Resources, Kyushu University

• Sakai Kentaro

  岡山県立大学 保健福祉学部栄養学科

• SHIRAI YOSHIHITO

  Department of Biochemical Engineering, Graduate School of Life Science and Systems Engineering, Kyus

• Mochizuki Satoshi

  Faculty Of Education And Welfare Science Oita University

• Umeki Miki

  Department Of Applied Chemistry Faculty Of Engineering Oita University

• Sakai Kentaro

  Dep. Of Nutrition And Health Promotion Fac. Of Human Life Sci. Hiroshima Jogakuin Univ.

• OUE Kazutoshi

  Department of Applied Chemistry, Faculty of Engineering, Oita University

• Sakai Kensuke

  Department Of Nutrition And Health Promotion Faculty Of Human Life Science Hiroshima Jogakuin Univer

• Oue Kazutoshi

  Department Of Applied Chemistry Faculty Of Engineering Oita University

• Shirai Yoshihito

  Department Of Biochemical Engineering Faculty Of Computer Science And System Engineering Kyushu Inst

• Shirai Yoshihito

  Department Of Biochemical Engineering And Science Faculty Of Computer Science And Systems Engineerin

• Sakai Kenji

  Department Of Environmental Chemistry And Engineering Faculty Of Engineering Oita University

• Shirai Yoshihito

  Deparment Of Food Science And Technology Faculty Of Agriculture Kyoto University

• Sakai Kenji

  Department Of Applied Chemistry Faculty Of Engineering Oita University

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