Removal of Organic Solvent from Antibiotics with Supercritical Carbon Dioxide

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概要

• 論文の詳細を見る

• Organic solvents were rapidly extracted from penicillin G potassium and streptomycin sulfate with supercritical carbon dioxide (SC-CO_2) at 200 atm and 35℃ without loss of antibiotic activities. The amounts of organic solvents remaining in the antibiotics depended upon pressure and temperature for a given extraction time. A semilogarithmic plot of remaining amounts of organic solvents against extraction time gave a straight line in the early extraction stage, allowing prediction of the extraction time required for decreasing amounts of organic solvent. The addition of water as an entrainer to SC-CO_2 resulted in a significant increase in extraction rates.

• 社団法人日本生物工学会の論文
• 1987-02-25

著者

• Kamihira M

  Department Of Biotechnology School Of Engineering Nagoya University

• Kamihira Masamichi

  Nagoya University:(present Office)kyushu University

• Kamihira Masamichi

  名古屋大学 工学研究科生物機能工学

• Kamihira Masamichi

  Department Of Biotechnology Graduate School Of Engineering Nagoya University

• KOBAYASHI Takeshi

  Department of Electrical Engineering, Faculty of Engineering Science, Osaka University

• Kamihira Masamichi

  Department Of Chemical Engineering Faculty Of Engineering Nagoya University

• Taniguchi M

  Fac. Engineering Niigata Jpn

• Taniguchi M

  Department Of Material Science And Technology Faculty Of Engineering

• Taiyouji Mayumi

  Gaduate School Of Science And Technology Niigata University:food Research Center Niigata Agricultura

• Taniguchi Masayuki

  Department Of Materials Science And Technology Niigata University

• TANIGUCHI MASAYUKI

  (Present address)Department of Chemical Engineering, Niigata University

• Kobayashi Takeshi

  Department Of Biological Chemistry College Of Bioscience And Biotechnology Chubu University

• Kobayashi T

  Dep. Of Biological Mechanisms And Functions Graduate School Of Bioagricultural Sciences Nagoya Univ.

• Tanaka Mitsuo

  Department Of Food Science And Technology Faculty Of Agriculture Kyoto University

• Kobayashi T

  Univ. Tsukuba Ibaraki Jpn

• Taniguchi Masayuki

  (present Address)department Of Chemical Engineering Faculty Of Engineering Nagoya University

• Kobayashi Takeshi

  Department Of Biotechnology Graduate School Of Engineering Nagoya University

• KOBAYASHI TAKESHI

  Department of Biotechnology, Faculty of Engineering, Nagoya University

• Takahashi Masafumi

  Department of Materials Science and Technology, Niigata University

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