<基礎的研究発生病理>SHRSPの高血圧性視神経乳頭浮腫と網膜, 脈絡膜血管障害

概要

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In SHRSP, the hypertensive papilledema appears when the cerebral stroke occurs. It is the purpose of this study to examine the pathological changes of the peripapillary choroid and pigment epithelium near the optic disc in SHRSP. Examination of the histological sections of SHRSP revealed that hypertensive changes were found in the choroidal vessels as well as the retinal vessels. Choroidal arteries showed marked changes of fibrinoid necrosis, and thrombosis of the lumen. Choriocapillaries were also occluded. The degeneration of the pigment epithelium was observed and the subretinal fluid contained phagocytosing cells near the optic disc in SHRSP. Such degeneration in the choroid and pigment epithelium may contribute to the development of hydropic changes of the peripapillary area in SHRSP.
近畿大学の論文
1986-12-30