高血圧性血管病変の発生病理 : SHRSPの睾丸における高血圧性血管病変(A 基礎的研究)(I 発生病理)

概要

論文の詳細を見る
Hypertensive vascular changes of the testes in SHRSP developed at a high incidence and from about 100 days of age. Therefore, after SHRSP of about 150 days of age with blood pressures of over 240 mmHg had their left testes removed, they had been given apresoline 80 mg/l in drinking water and 30% casein diet for 8 to 12,58,92,127. or 169 days. Hypertensive vascular changes of the left testes before treatment were compared with those of the right testes after treatment both histologically (by cross-sectioning/each of them at the same four locations) and electronmicroscopically. 1) When compared with the number of vessels with hypertensive vascular changes before treatment, there were no increases after antihypertensive treatment. 2) After antihypertensive treatment, arterioles with fibrinoid degeneration and lumen reduction increased. On the other hand, new deposits of fibrinoid material were not found in arterioles with thickened walls ; their lumen was also maintained. 3) After antihypertensive treatment, deposits of fibrinoid materials were controlled in small arteries, while granulation around the fibrinoid necrosis and it's increase with maturation were accelerated.
近畿大学の論文
1980-09-25