植物中の降圧物質について(第三報)(II 予防および治療)(A 基礎的研究)

概要

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The hypotensive effects of hot water extracts from twenty-four weeds were examined by using SHR and SHRSP. Intravenous administration of the extracts from Solidago altissima L., Lespedeza cuneata G. Don., Macleya cordata R. Br. and Trifolium repens L. showed marked falls of blood pressure in SHR and SHRSP. Especially, the extract from Solidago altissima L. was recognized to have continuous depressive effect. Then, we tried to investigate the effects of Solidago altissima L. on the blood pressure of SHR and SHRSP. The following results were obtained. (1) When the fractions from flowers and leaves of Solidago altissima L. were intra venously administered, the blood pressure of SHR and SHRSP showed marked falls, but the fractions from stems and roots were not recognized to have depressive effects. (2) The fraction from leaves of Solidago altissima L. having a potent hypotensive effect was found after void fraction by gel filtration of Sephadex G-75. This fraction was qualitatively positive in Leaberman-Barchard reaction and H_2SO_4 reaction.
近畿大学の論文
1981-09-25