レモン, 温州みかんおよびオレンジ果皮中のフェニルプロパノイド配糖体の構造および生理活性(II 予防および治療)(A 基礎的研究)

概要

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An attempt was made to study on physiolosically active phenyl propanoid glycosides in citrus peels. The six phenyl propanoid glycosides were isolated by repeating chromatography on silica get and get filtration after extracting with n-butanol and treating with lead subacetate. Their structures were established as coniferin (1), syringin (2), biconiferylalcohol 1-β-glucopyranoside (3), citrusin A (4), citrusin B (5) and eugenol 1-β-glucopyranoside (6) by MS, UV, ^1H-NMR and ^<13>C-NMR spectroscopy and chemical evidence. Then each component was intravenously injected in SHR-SP (1mg/100g body weight), and compound 1 and 2 were found to rise the rat blood pressure, but compound 3,4 and 6 were found to lower the pressure. Among these compounds isolated in the present study, compound 3,4,5 and 6 were found to be new phenyl propanoid glycosides.
近畿大学の論文
1985-12-30