植物成分の合成化学的研究による生物活性物質の開発

概要

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The components in eleven kinds of citrus fruit peelings and hinoki cypress leaves were studied in order to develop the biological active substances, and eighty-six components including thirty-eight new compounds were isolated. Furthermore, several flavonoid glycosides and phenyl propanoid glycosides having a biological activity such as hypotensive or hypertensive effect were found. The important relations between the biological active substances and their structures are described. The new efficient methods were developed for the synthesis of biological active substances, for example, <I>l</I>-periryl alcohol, <I>R</I>-homocamphenilone, nojigiku alcohol, biguaiazulenone, and guaiazulenequinone from readily available, natural terpenoids, azulenoids, and the re-lated compounds.
社団法人有機合成化学協会の論文