<予防および治療>急性血圧上昇によるラット脳波像の変化

概要

論文の詳細を見る
Sixteen female SD rats weighing 200-220 g were used. Intraperitoneal injection of ketamine hydrochloride induced a sleep EEG pattern with periodic appearances of slow wave discharges. A rapid blood pressure increase, produced by epinephrine injection, induced a distinct elongation and higher incidence of discharges. Comparisons with the time course of the blood pressure change showed a phase-lag relationship in the pattern changes of slow wave grouping. Power spectrum analysis also showed a distinct increase in the 2-5 Hz range in an abrupt increase in the blood pressure. The observation indicated that the dominant manifestation of slow wave grouping in the hypertensive state is closely relating to the increase in intracranial pressure due to hypertension.
近畿大学の論文
1988-12-30