M-SHRSPおよびその諸種交雑子孫の血圧, 脳病変その他について第3報 M-SHRSPとSHC(今井ら)の交雑子孫について(I 発生病理)(A 基礎的研究)

概要

論文の詳細を見る
Various crossings or backcrossings using M SHRSP, SHC, and their crossbred offspring were performed and blood pressures, plasma cholesterol levels and other characteristics were examined. The blood pressures and plasma cholesterol levels of crossbred offspring of M-SHRSP and SHC were intermediate to those of M-SHRSP and SHC and, through continuous backcrossings. tended to come closer to those of either M-SHRSP or SHC. There was a tendency for the rats obtained through continuous successive selective brother-sister breeding of those with hypertension and noticeable hypercholesterolemia selected from the M-SHRSP and SHC crossbred offspring to suffer from marked hypertension, noticeable hypercholesterolemia and enlargement of the kidneys. Calcium deposits were found in the aorta of a small number of such rats.
近畿大学の論文
1983-12-30