<予防および治療>M-SHRSPの降圧剤投与による眼底変化

概要

論文の詳細を見る
Using M-SHRSP, the therapeutic effects of captopril alone or in combination with hydralazine hydrochloride were studied ophthalmoscopically. In proportion to the hypotensive effects, ophthalmoscopic scores of general narrowing or caliber irregularity of retinal arterioles showed marked effects in the combined therapy group. In the captopril alone group, there was a slight decrease in the blood pressure from 20 to 30 mmHg. Howerer, the rats lived markedly longer than those in the non-treated group and as long as those in the combined therapy group. The retinal arterioles, if captopril prevents the severe rise in blood pressure for a certain period, may adapt themselves to their hypertensive environment and maintain their retinal functions.
近畿大学の論文
1992-12-30