<原著>異常条件下におけるSulpirideの腸管吻合におよぼす影響について

概要

論文の詳細を見る
Canalis and Ravitch observed that if the anastomosis was partially isolated from the peritoneal cavity by wrapping with Silastic gauze, the result was almost invariably leakage peritonitis and death, irrespective of the anastomotic technique employed. The aim of this study was to use this technique of isolating the anastomosis with Marlex mesh to evaluate whether Sulpiride had a favorable effect on wound healing of the intestine or not. As far as the result of this study is concerned, Sulpiride had a better effect on the topical circulation in colonic anastomosis than that of the control group. It seems that Sulpiride has a good influence on the wound healing of intestinal anastomosis. On the basis of available result, it seems reasonable to use Sulpiride clinically after the anas tomosis of alimentary tract. In the overall estimation of wound healing under an unusual condition, there was no significant difference between the control and the Sulpiride administration group. These results suggest that other important factors, for example, the correction of inflammation or postoperative metabolism should be concerned significantly in the intestinal wound healing.
近畿大学の論文
1979-09-25