<原著>非特異性多発性小腸潰瘍 : 本邦報告92例についての考察

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The diagnosis of primary small bowel ulceration is made by the demonstration of characteristic ulcer (s) in the absence of any underlying disease. The clinical course of primary small bowel ulcer is poorly understood and, until the cause is defined, the factors which influence the progression or healing of these lesions will remain unknown. As for so-called non-specific multiple ulcers of the small intestine by Okabe, et al. (1966), whether this is one of the new disease entities or an atypical type of another disease still remains unresolved. According to Yao, et al. (1979), an ulcerative, non-proliferative disease of small intestine ; non-specific multiple ulcers of the small intestine are seen in young adults, and its main symptoms include occult blood in the stool, anemia, hypoproteinemia and abdominal pain. Almost all of the patients have the clinical course of long duration. Macroscopic pictures of this disease are characterized by several stenosis, multiple shallow ulcers developing crosswise or obliquely on the intestinal mucosa and none of perforation, fistula formation, obstruction or abscess. Microscopic examination shows multinle ulcers mostly confined to the submucosal layer. We reviewed 92 cases of non-specific multiple ulcers of the small intestine in the Japanese literature, and gained the similar characteristic results. However, several cases that differ from the definition of Okabe, et al. were also seen, and it may suggest that these ulcers are not classifed into a new disease entity yet. Since there is some confusion on the clinical and the pathohistological diagnosis of these ulcers, clear criteria for the diagnosis should be established.
近畿大学の論文
1980-12-25

<原著>非特異性多発性小腸潰瘍 : 本邦報告92例についての考察

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