<原著>肺癌におけるTissue Polipeptide Antigenの臨床的検討(第1報)

概要

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The serum value of tissue polipeptide antigen (TPA) was measured mainly for patients with lung cancer, and its possible correlation to other tumor markers was investigated. The following results were obtained. 1. The serum value of TPA of healthy subjects was 99.0±33.5 U/l. There was no difference between male and female subjects. Smokers showed higher TPA values than non-smokers. 2. Patients with lung cancer or other malignant tumors revealed significantly higher TPA values than healthy subjects (p<0.01) or patients with chronic bronchitis (p<0.05). Even more than 1,500 U/l was detected in some of the patients with lung cancer. There were some non-tumor cases showing high TPA values. 3. As for the relation to other tumor markers, TPA value was directly proportional to serum ferritin (R=O.632,p<0.05). There was no evident correlation between TPA value and serum CEA or AFP value. 4. Serum TPA value was indicative of the result of treatment and prognosis of lung cancer. The results obtained from the present study suggest that the serum value of TPA can be utilized for diagnosing malignant tumor in combination with other tumor markers.
近畿大学の論文
1984-03-25