植物中の降圧物質について(第二報)(A 基礎的研究)(II 予防および治療)

概要

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The hypotensive effects of hot water extracts of various plants, daily foods, medicines, garden plants and citrus fruits were examined by using SHR and SHRSP. The following results were obtained. 1. Intravenous administration of fractions from citrus peels (lemon, kumquat, grapefruit, yuzu, orange, iyokan, narutokan, sudachi and mandarin orange) showed marked falls of blood pressure in SHR and SHRSP. Stronger hypotensive effects were found in those fractions with molecular weights of 300 to 1,000. 2. Both low and high molecular fractions of extracts of bamboo leaves showed hypotensive effects. but the effect of the latter was more potent. The molecular weight of this fraction was under approximately 10,000 ; it was qualitatively positive in a ninhydrin reaction and with the phenol-H_2SO_4 method. 3. The effective substances in the corn extracts (cornhusk, corncob and tassel) had low molecular fractions. The cornhusk was the most effective of the extracts examined. 4. Low molecular fractions of extracts from chlorella raw cells were recognized to have a depressive effect. The blood pressures of SHR and SHRSP showed marked falls when this fraction was injected intravenously.
近畿大学の論文
1980-09-25