高血圧ラットの動脈壁における酸性およびアルカリ性フォスファターゼ活性の変動

概要

論文の詳細を見る
The effects of antihypertensive treatment on the alkaline and the acid phosphatase activity in the vascular wall of SHRSP were examined. Both the alkaline and the acid phosphatase activity were higher in the mesenteric artery than in the aorta. In the aorta of 6 month-old SHRSP, alkaline phosphatase activity was similar to but acid phosphatase activity was higher than in the aorta of 3 month-old SHRSP, whereas such age-related changes were opposite in the mesenteric artery. These activities were lower both in the aorta and the mesenteric artery of the SHRSP treated with reserpine or hydralazine than in those of the untreated control. These results indicate the important role of these enzymes in different manners for hypertension and hypertensive vascular changes.
近畿大学の論文
1987-12-30