Na減量栄養液におけるCa拮抗薬(VerapamilおよびDiltiazem)の作用(ラット門脈における実験)(A 基礎的研究)(II 予防および治療)

概要

論文の詳細を見る
By using the isolated portal vein from rats, the effects of the Ca antagonists (diltiazem and verapamil) on the responses to the smooth muscle contractile agents (K, acetylcholine, noradrenaline and Ba) were investigated in the normal and Na-decreased media, and the following results were obtained. 1. The Ca antagonists tested inhibited with a dose-dependent manner the responses to the contractile agents tested in the normal and Na-decreased media. 2. The inhibitory effects of the Ca antagonists on the responses to the contractile agents were larger in the Na-decreased medium than in the normal medium. 3. The Ca antagonists showed the strongest inhibition against the contraction by K and showed the weakest inhibition against the contraction by Ba. The inhibitory effects against the contractions by acetylcholine and noradrenaline were almost the same.
近畿大学の論文
1980-09-25