<原著>モルモット摘出精嚢におけるK, acetylcholine, noradrenalineおよびBaの収縮機序, とくにCaとの関連

概要

論文の詳細を見る
Using the strips of seminal vesicle from guniea pig, the contractile mechanisms of K, acetylcholine (ACh), noradrenaline (NA) and Ba were investigated in relation to the mobilization of Ca. 1. Shapes of the contractile responses to K, ACh, NA and Ba consisted of the phasic contraction (PC) and the subsequent tonic contraction (TC). TCs and PCs by ACh, NA and Ba are induced by the release of Ca from the storage sites. PC by K is induced by the passive Ca influx and the Ca release, and TC by K is maintained by the passive and active Ca influxes and the Ca release. 2. In the muscle cell membrane, there are three divisions of Ca stores : the first is the store where Ca is most easily released, the second is the store where Ca is comparatively easily released and the third is the store where Ca is not easily released. K releases Ca from the first store, ACh and NA do so from the first and the second stores, and Ba does so from these three stores for producing contraction. 3. Contrations by exogenous Ca in Ca-free bathing solution are produced by the passive Ca influx in the low concentration of Ca and in the high concentration of Ca by the participation of the active Ca influx in addition.
近畿大学の論文
1976-11-30