平滑筋収縮薬の作用におよぼす平滑筋弛緩薬の作用(SHRSPの門脈における実験)(II 予防および治療)(A 基礎的研究)

概要

論文の詳細を見る
Effects of some spasmolytics, using the isolated portal veins from SHRSP and WKY, were investigated on the responses to the smooth muscle contractile agents (K, Ba, ACh and noradrenaline), and the following results were obtained. 1. Dibutyryl C. AMP, a sympathetic beta stimulant, fenoterol, a phosphodiesterase inhibitor, papaverine or aminophylline, inhibited the responses to the contractile agents with a dose-dependent manner. The inhibitions were larger in WKY than in SHRSP. 2. A Ca antagonist, diltiazem, inhibited the response to the contractile agents with a dose- dependent manner. The inhibition was larger in SHRSP than in WKY. 3. The above-mentioned results were compared with between SHRSP and WKY, and were discussed from the respect of the sensitivity of beta receptor and the Ca availability.
近畿大学の論文
1981-09-25