<Originals>Inhibitory effects of traditional crude drug extracts on the nasal allergy induced by ovalbumin in the guinea pig
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概要
- 論文の詳細を見る
Fifty percent methanol extracts of Gaiyo, Ogi, Zentai, Hishi and Biwayo possessing antidegranulation activities on the mast cells were examined for anti-allergic effects in guinea pigs with nasal allergy. Each of the symptom scores for the nasal allergy and histamine contents in the nasal mucosa of guinea pigs after provocation of ovalbumin (antigen) was compared to the crude drug treated animals. The nasal allergic scores were significantly decreased by Gaiyo, Ogi, Biwayo, Zentai and Hishi extracts in descending order. The histamine content in the nasal mucosa was markedly inhibited by Gaiyo, Ogi and Biwayo extracts. These findings indicated that these 5 traditional crude drugs possessed very strong antiallergic actions not only in in vitro, but also in in vivo experiment.
- 近畿大学の論文
著者
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Higashino Hideaki
Department of Pharmacology, Kinki University School of Medicine
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Higashino Hideaki
Department Of Pharmacology Kinki University School Of Medicine
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SUZUKI Aritomo
Department og Pharmacology, Kinki University School of Medicine
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HIRAZAWA Masako
Department of Otolaryngology, Kinki University School of Medicine
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MURATA Kiyotaka
Department of Otolaryngology, Kinki University School of Medicine
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Suzuki Aritomo
Department Of Parasitology And Department Of Pharmacology
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Murata Kiyotaka
Deparment Of Otolaryngology Kinki University School Of Medicine
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Hirazawa Masako
Department Of Otolaryngology Kinki University School Of Medicine
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Higashino Hideaki
Department Of Pharmacology Kinki University Faculty Of Medicine
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