<Originals>The Relaxation Mechanism of Papaverine and Aminophylline in Vas Deferens of Guinea Pig, Particularly in Relation to Ca
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概要
- 論文の詳細を見る
By using the isolated vas deferens of guinea pig, the relaxation mechanisms of papaverine and aminophylline were investigated in relation to the Ca mobilization and the following results were obtained. 1. The low concentrations of papaverine and aminophylline showed the preferential inhibition against the tonic contraction in the K-induced contraction and the high ones also inhibited the phasic contraction in addition. 2. The low concentration of papaverine inhibited only the contraction by the high concentrations of Ca but did not inhibit that by the low concentrations of Ca. But the high concentration of papaverine also inhibited the contraction by the low concentration of Ca in addition. 3. The low concentration of aminophylline inhibited the contractions by the low and high concentrations of Ca. 4. The effects of the low concentration of papaverine and aminophylline and the high concentration of aminophylline were remarkably inhibited in the depolarization by the high K, but that of the high concentration of papaverine was hardly affected. 5. These results were discussed from the standpoint of the Ca mobilization.
- 近畿大学の論文
- 1980-06-28
著者
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Yanagawa Takao
Department of Cardiology, Niigata University Graduate School of Medical and Dental Sciences
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Kondo Shinichi
Department Of Clinical Laboratory Kobe University Hospital
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Higashino Hideaki
Department of Pharmacology, Kinki University School of Medicine
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Yanagawa Takao
Department Of Cardiology Niigata City General Hospital
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Yanagawa Takao
Department Of Pharmacology Kinki University School Of Medicine
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Higashino Hideaki
Department Of Pharmacology Kinki University School Of Medicine
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SUZUKI Aritomo
Department og Pharmacology, Kinki University School of Medicine
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Suzuki Aritomo
Department Of Parasitology And Department Of Pharmacology
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Kondo Shinichi
Department Of Chemistry Faculty Of Engineering Gunma University
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Higashino Hideaki
Department Of Pharmacology Kinki University Faculty Of Medicine
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Kondo Shinichi
Department Of Bioscience Research Tsukuba Research Laboratory Toagosei Co. Ltd.
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Kondo Shinichi
Department Of Pharmacology Kinki University School Of Medicine
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Kondo Shinichi
Department Of Biochemistry Graduate School Of Biomedical Sciences Hiroshima University
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YANAGAWA Takao
Department of Pharmacology, Kinki University School of Medicine
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KONDO Shinichi
Department of Bioactive Molecules, Institute of Microbial Chemistry
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