A POSSIBLE MECHANISM OF INFERTILITY BY ACUTE CADMIUM INTOXICATION
スポンサーリンク
概要
- 論文の詳細を見る
A possible mechanism of infertility by Cd was investigated from the standpoint of influence of Cd on the contractile responses of isolated seminal vesicle from guinea pigs to K, acetylcholine, noradrenaline, Ba and Ca by using the Magnus method. Cd inhibited the contractile responses to the contractile agents tested in a dose-dependent manner. Cd showed the preferential inhibition against the contractile responses to K and Ca. The inhibitory effect of Cd on the contractile responses to noradrenaline and acetylcholine was hardly removed. The effect of Cd was inhibited by the thiol compounds, glutathione and thiola. The active mechanism of Cd was discussed in relation to Ca mobilization.
- 日本トキシコロジー学会の論文
- 1978-11-15
著者
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Yanagawa Takao
Department of Cardiology, Niigata University Graduate School of Medical and Dental Sciences
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Sugimoto Jiro
Department Of Pharmacology Kansai Medical School
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Yanagawa Takao
Department Of Cardiology Niigata City General Hospital
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Yanagawa Takao
Department Of Pharmacology Kinki University School Of Medicine
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SUZUKI Aritomo
Department og Pharmacology, Kinki University School of Medicine
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Suzuki Aritomo
Department Of Parasitology And Department Of Pharmacology
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KAJIMOTO Noriyoshi
Departments of Pharmacology, Kinki University School of Medicine
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Kajimoto Noriyoshi
Department Of Pharmacology Kinki University School Of Medicine
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NAGATA Mitsuhiro
Department of Pharmacology, Kansai Medical School
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Nagata Mitsuhiro
Department Of Pharmacology Kansai Medical School
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