2, 3 diphosphoglycerate (2, 3DPG) values in stroke-prone spontaneously hypertensive rats (SHRSP):Its relationship to aging
スポンサーリンク
概要
- 論文の詳細を見る
Because 2, 3DPG is one of the main factors which are concerned with the affinity of Hb for oxygen and 3PG is the degrading metabolite of 2, 3DPG, there are three following possibilities in SHRSP: 1) in pulmonary tissues the diffusion of oxygen may be interfered to some extent (cf. results 1 & 2), 2) in peripheral tissues the less releasing of oxygen from Hb may cause oxygen deficiency (cf. results 3 & 4) and therefore, these findings may be the underlying factors which cause hypertension (cf. result 6), and 3) the inability of producing 2, 3DPG may result in the decreased tolerance under oxygen deficiency, and the process of production or degradation of 2, 3DPG in SHRSP must have some defects.
- International Heart Journal刊行会の論文
著者
-
Yanagawa Takao
Department Of Cardiology Niigata City General Hospital
-
Suzuki Aritomo
Department Of Parasitology And Department Of Pharmacology
-
Higashino Hideaki
Department Of Pharmacology Kinki University Faculty Of Medicine
関連論文
- PJ-474 The Effects of Erythropoietin-derivatives on Monocrotaline-induced Pulmonary Hypertension in Rats(PJ080,Pulmonary Circulation 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-724 Asialoerythropoietin showed cardioprotective effects on ischemia-reperfusion injury model in mouse(Myocardial ischemia / reperfusion, basic / clinical(04)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation
- OJ-179 Asialoerythropoietin is a Hopeful Drug for Angiogenesis Therapy(Regeneration (angiogenesis / myocardial regeneration)-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Angiotensin Converting Enzyme Inhibitor Reduces Cardiac Hypertrophy and Fibrosis in Cardiomyopathic Hamsters via NO-dependent Mechanisms(Heart Failure, Basic 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Dynamic Intraventricular Obstruction in Acute Myocardial Infarction With Administration of Cilostazol
- Reactivity of Intrarenal Arteries to Vasoconstrictor and Vasorelaxant Polypeptides in Adult Stroke-Prone Spontaneously Hypertensive Rats
- Implication of platelets in the course of immediate asthmatic response in anaphylactic bronchial asthma of guinea pigs
- The effects of vasocontractile agents on pulmonary artery of stroke-prone spontaneously hypertensive rats (SHRSP), in relation to aging and hypertension
- Glycation Decreases the Stability of the Triple-Helical Strands of Fibrous Collagen against Proteolytic Degradation by Pepsin in a Specific Temperature Range
- The Mechanism of Interaction of Sodium Dodecyl Sulfate with Elastic Fibers
- Endothelin participates in a process of fibrinogen-involved platelet aggregation
- Upper shift of the set point in the thermocenter causes hyperthermia in SHRSP
- Responses to vasocontractile agents in the renal arteries and the aortas of stroke-prone spontaneously hypertensive rats (SHRSP), with special reference with aging
- Inhibitory effects of traditional crude drug extracts on the nasal allergy induced by ovalbumin in the guinea pig
- Thermo-elevation effect on blood flow in stroke-prone spontaneously hypertensive rats (SHRSP)
- Characterization of dopamine-induced vasorelaxation in isolated renal arteries from stroke-prone spontaneously hypertensive rats
- Influence of L-NNA and GTN on blood pressure and heart rate in conscious SHRSP and WKY
- Influence of endothelin-1 on systolic arterial pressure and heart rate in conscious WKY and SHRSP
- A trial of chronic administration of Siamese Momordica charantia and Phyllanthus urinaria powders to streptozotocin-induced diabetic rats
- Age-related changes in serum and tissue angiotensin converting enzyme activities in SHRSP and WKY
- Effects of Isoteoline on the blood pressure and renin-angiotensin system in spontaneously hypertensive rats
- Influence of Nivalin P on the training and memorizing processes in rats
- Pharmacological and toxicological study of newly synthesized 1,3-dimethylxanthine derivatives
- Alpha-1 adrenergic function in hemodynamic control of stroke-prone spontaneously hypertensive rats (SHRSP)
- The responses to various relaxing substances in the renal arteries and the aortas of stroke-prone spontaneously hypertensive rats (SHRSP) at various ages
- Decreased Expression of Catechol-O-Methyltransferase in the Renal Cortex of Malignant Spontaneously Hypertensive Rats
- Effects of Sodium Nitrite on the Contractions in the Vas Deferens from Guinea Pig
- Effects of Methylene Blue and Acridine Orange on the Contraction in the Vas Deferens from Guinea Pig
- Effects of pH and Temperature on Drug-Induced Contractions in the Isolated Guinea Pig Vas Deferens
- Effects of Local Anesthetics on the Responses to Some Contractile Agents, Especially in Relation to Ca
- A Possible Mechanism for Cadmium-Induced Hypertension in Rats
- A review on the properties and applications of perfluorocarbon emulsions
- A CALCIUM ANTAGONIST, NB-818, IMPROVES BLOOD FLOW DISTRIBUTION IN THE BRAIN AND OTHER MAJOR ORGANS OF STROKEPRONE SPONTANEOUSLY HYPERTENSIVE RATS (SHRSP)
- The Relaxation Mechanism of Papaverine and Aminophylline in Vas Deferens of Guinea Pig, Particularly in Relation to Ca
- Effect of endothelins on the fibrinogen-involved aggregation process in platelets of guinea pig
- A POSSIBLE MECHANISM OF INFERTILITY BY ACUTE CADMIUM INTOXICATION
- Suppression of the descending inhibitory pathway by continuous thoracic intrathecal lidocaine infusion reduces the thermal threshold of the tail-flick response in rats
- EFFECTS OF CADMIUM ON THE TENSION OF ISOLATED RAT AORTA (A POSSIBLE MECHANISM FOR CADMIUM-INDUCED HYPERTENSION)
- Diabetic Retinopathy and α_2-Macroglobulin
- Contractile Mechanism of ATP in Isolated Vas Deferens of Guinea Pigs
- Responses to seven vasorelaxant neuropeptides in small renal arteries isolated from stroke prone spontaneously hypertensive rats
- Inhibitory Effect of Chlorpromazine on the Myocardial Contractility
- Comparative Studies on Inhibition of the K-Induced Tonic Contraction in Guinea Pig Vas Deferens by Chlorpromazine, Zotepine and their Free Radicals
- Antinociceptive action of carbamazepine on thermal hypersensitive pain at spinal level in a rat model of adjuvant-induced chronic inflammation
- Mechanism of the Contracting Actions of K, Acetylcholine, Histamine, Noradrenaline and Ba in the Excised Vas Deferens of Guinea Pig, Particularly in Relation to Ca
- Effects of cholecalciferol and calcium on experimental hepatic osteodystrophy in rats
- The Contractile Mechanism of Acetylcholine in the Isolated Seminal Vesicle of Guinea Pig, Particulary as to the Catecholamine Release
- Norepinephrine Sensitivity, Reactivty and Neuronal Uptake in the Isolated Vas Deferens from SHRSP and WKY
- Influence of Ca Contents in the Medium on the Responses to the Smooth Muscle Contractile Agents in the Isolated Vas Deferens from SHRSP
- The Modification of the Responses to Noradrenaline and Acetylcholine by Aging and the Effects of Some Smooth Muscle Relaxants on the Smooth Muscle Contractile Drugs:Experiment in the Isolated vas Deferens of SHRSP and Wistar-Kyoto Rats
- Synthesis and Metabolism of Dopamine in Kidney Slices of Stroke-Prone Spontaneously Hypertensive Rats
- On the Hypotensive Flavonoids in Young Barley Leaves (Part 2). Di-C-gluco-sylflavone
- On the Hypotensive Substances in Chlorella Extract
- On the Hypotensive Substances of Bamboo Leaves
- Effects of vasodilators on the tonus of aortas from SHRSP and WKY, especially in relation to aging
- The enhanced effects of adrenaline and serotonin on ADPinduced platelet aggregation in SHRSP
- A Study on the Hyperthermia in SHRSP; a Comparison with WKY in Body Temperature (the Second Report)
- Comparison of Platelet Aggregation Activities between SHRSP and WKY, with Special Reference to Aging
- Measurements of Intracellular Free Calcium Levels in Platelets of SHRSP and WKY and Possible Relation to Its Aggregation Potency
- Spare receptor in the isolated blood vessels from SHRSP
- Abnormal responses to the vasoconstrictor sgents in isolated aortas from SHRSP, especially in relation to aging
- Spare Receptors in Aortas from Stroke-Prone SHR and WKY
- Hypertensive Mechanism of Cadmium (Experiment in The isolated Aorta from SHRSP)
- Comparative Studies on the Structure of Extracellular Matrix in Aortic Walls of SHRSP and WKY
- The relaxation responses of superior mesenteric arteries of SHRSP, with special references to aging
- Effect of Ca2+ Contents in Medium on the Responses to Some Contractile Agents in Isolated Portal Veins from SHRSP and WKY
- Antihypertensive and Other Pharmacological Effects of the Calcium Antagonist, NB-818, in 2- and 6-month-old SHRSP
- Effects of Some Spasmolytics on The Responses to The Smooth Muscle Contractile Agents:Experiment in The Isolated Portal Vein from SHRSP
- On the Hypotensive Substances in Plants:(2) Fractionation of Plant Extracts and Mechanism of Their Action
- Changes in Ca-ATPase Activity and Ca Uptake Rate of Heart Muscle SR of the Stroke-Prone SHR in Relation to Aging
- Reactivity to receptor and Ca2+ availability in vascular smooth muscle from SHRSP
- 2, 3 diphosphoglycerate (2, 3DPG) values in stroke-prone spontaneously hypertensive rats (SHRSP):Its relationship to aging
- Responses of isolated renal arteries in SHRSP to vasodilators and transmural electrical stimulation
- Cerebral Arterial Disorder in SHRSP:The Determination of Cells and Various Connective Tissues
- Comparison of the Direct and Indirect Measurements for Blood Pressure and Heart Rate in Relation to the External Temperature in 12-month-old SHRSP and WKY
- Effect of Hypoxia on the Physiological States of SHRSP and WKY
- Response to Vasoactive Neuropeptides in Basilar Arteries Isolated from Stroke-Prone Spontaneously Hypertensive Rats
- Responses to noradrenaline, phenylephrine and clonidine in the vascular smooth muscle of SHRSP
- 2, 3Diphosphoglycerate (2, 3DPG) Production-degradation Systems in SHRSP and WKY
- Depressor and pressor effects of endothelin-1 and endothelin-3 in conscious WKY and SHRSP
- Vasorelaxation Response of Basilar Arteries Isolated from Stroke-Prone Spontaneously Hypertensive Rats
- Hypotensive Effects of the Siamese Plants on SHRSP:Imperata Cylindrica and Phyllanthus Emblica Extracts
- Relaxant Effects of Calcitonin Gene-related Peptide on Isolated Small Renal Arteries in Stroke-Prone Spontaneously Hypertensive Rats.
- Alpha-1 Adrenergic Function in Hemodynamic Control of Stroke-prone Spontaneously Hypertensive Rats (SHRSP)
- Effects of Calcium Antagonist, NB-818, on the Regional Hemodynamics in Conscious 6-month-old SHRSP and WKY
- The Effect of ONO-3144 on the Prolongation of Life-Span in SHRSP
- Effect of cadmium ions on the tension of isolated vascular smooth muscles from SHRSP
- Effects of L-NNA and GTN on blood pressure and heart rate in conscious SHRSP and WKY
- Effects of nitroglycerin on stable thromboxane A2 analogue-induced, nifedipine-resistant contraction in canine basilar artery.
- Age-related Changes in Platelet Aggregation Activity and Some Drug Modification on Platelet Function
- Altered Relaxation of the Isolated Aortas in Aging and Hypertension
- The Reactivity of Vascular Smooth Muscle in Stroke-Prone SHR, especially from the Standpoint of Aging
- Effects of Cadmium in the Isolated Vascular Smooth Muscle from WKY and SHRSP
- NORADRENALINE-INDUCED BIPHASIC RESPONSES IN PULMONARY ARTERIES OF YOUNG STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS:ROLE OF ENDOTHELIUM
- The Changes in Angiotensin Converting Enzyme Activities to Hypertension in SHRSP and WKY
- Relaxant Response of Isolated Basilar Arteries to Calcitonin Gene-Related Peptide in Stroke-Prone Spontaneously Hypertensive Rats.
- Glycation Decreases the Stability of the Triple-Helical Strands of Fibrous Collagen against Proteolytic Degradation by Pepsin in a Specific Temperature Range.