<Originals>A trial of chronic administration of Siamese Momordica charantia and Phyllanthus urinaria powders to streptozotocin-induced diabetic rats
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概要
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The chronic hypoglycemic effects of two Thai medicinal plants, Momordica charantia (M.c.) and Phyllanthus urinaria (P.u.), were tested in streptozotocin-induced diabetic rats. Although both plant powders caused strong hypoglycemic effects in the diabetic rats, the rats administered a high dose of M.c. showed a significant decrease in body weight and a high mortality rate (37.5%) in four weeks. On the other hand, P.u. had a more preferable hypoglycemic effect in the diabetic rats. These findings indicate that M.c. should be used clinically with special care, because it may contain phlorizin-like toxic substance.
- 近畿大学の論文
著者
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Higashino Hideaki
Department of Pharmacology, Kinki University School of Medicine
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Higashino Hideaki
Department Of Pharmacology Kinki University School Of Medicine
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SUZUKI Aritomo
Department og Pharmacology, Kinki University School of Medicine
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Suzuki Aritomo
Department Of Parasitology And Department Of Pharmacology
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Higashino Hideaki
Department Of Pharmacology Kinki University Faculty Of Medicine
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