Reactivity to receptor and Ca2+ availability in vascular smooth muscle from SHRSP
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概要
- 論文の詳細を見る
The reactivity to receptors and the Ca2+ availability in some vascular smooth muscles from SHRSP and WKY were investigated. (1) The affinity and the intrinsic activity (Ca2+ mobilization activity) to adrenaline receptor in femoral, mesenteric and renal arteries were not different between SHRSP and WKY. (2) The affinity to angiotensin receptor in thoracic aorta, portal vein and renal and mesenteric arteries is not different between SHRSP and WKY. But, the intrinsic activity to angiotensin receptor in thoracic aorta is decreased and that in mesenteric, renal arteries and portal vein is increased. (3) The reactivities to beta receptor and/or to C. AMP are increased in thoracic aorta and renal artery from SHRSP, while that in portal vein is decreased, being no change in femoral and mesenteric arteries. (4) The Ca2+ mobilization activity (Ca2+ influx and Ca2+ release) are accelerated in thoracic aorta and portal vein from SHRSP.
- International Heart Journal刊行会の論文
著者
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Yanagawa Takao
Department Of Cardiology Niigata City General Hospital
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Murakami Noriko
Department Of Parasitology And Department Of Pharmacology
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Niwa Atsuko
Department Of Immunology Kinki University School Of Medicine
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Suzuki Aritomo
Department Of Parasitology And Department Of Pharmacology
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Kajimoto Noriyoshi
Department Of Pharmacology Kinki University School Of Medicine
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Higashino Hideaki
Department Of Pharmacology Kinki University Faculty Of Medicine
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Murakami Noriko
Department of Life Sciences, Faculty of Agriculture, Kagawa University
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