THE EFFECT OF THIAMINE TETRAHYDROFURFURYLDISULFIDE AGAINST POTASSIUM LOSS IN ISOLATED GUINEA-PIG ATRIA
スポンサーリンク
概要
- 論文の詳細を見る
Spontaneous contractions of isolated guinea-pig atria were arrested in a potassium free medium. But, the time required to arrest atrial contractions was prolonged, when the potassium free medium contained thiamine tetra-hydrofurfuryldisulfide (TTFD). Dimethialium propyldisulfide (DMPD) showed the similar effect, while thiamine or thiamine pyrophosphate (TPP) did scarcely. Potassium content in the atria kept in a potassium free medium reduced, but the reduction was prevented by the presence of TTFD contained in the medium. DMPD, thiamine, or TPP could hardly show the similar effect. TTFD is a derivative of thiamine and has a disulfide form in its chemical structure. These specialities were assumed to bring about the above two kinds of effects of TTFD.
- 1972-11-20
著者
-
Sugimoto Jiro
Department Of Pharmacology Kansai Medical School
-
Nagata Mitsuhiro
Department Of Pharmacology Kansai Medical School
-
FUGONO REIKO
Department of Pharmacology, Kansai Medical School
-
Fugono Reiko
Department Of Pharmacology Kansai Medical School
関連論文
- A POSSIBLE MECHANISM OF INFERTILITY BY ACUTE CADMIUM INTOXICATION
- COMPARATIVE STUDIES ON THE PHARMACOLOGICAL ACTIONS OF ANTI-ARRHYTHMICS IN ISOLATED GUINEA-PIG ATRIA
- Strophanthin-G Toxicity and Sodium Ions
- THE EFFECT OF THIAMINE TETRAHYDROFURFURYLDISULFIDE AGAINST POTASSIUM LOSS IN ISOLATED GUINEA-PIG ATRIA
- SPECIFICITY OF MUSCLE RESPONSE OF THE JAPANESE MEDICAL LEECH TO ACETYLCHOLINE
- Influence of Magnesium Ions on Calcium-influx and Release of Tissue Calcium Ions in the Smooth Muscle of Isolated Guinea-pig Vas Deferens
- Calcium-induced Contraction in the Isolated Guinea-Pig Vas Deferens Pretreated with Tetrasodium Edetate
- BIOTRANSFORMATION OF THIAMINE TETRAHYDROFURFURYLDISULFIDE AND ITS EFFECT ON POTASSIUM LOSS IN ISOLATED GUINEA-PIG ATRIA
- THE ROLE OF CALCIUM, POTASSIUM AND SODIUM IONS ON THE NORADRENALINE INDUCED CONTRACTION IN THE VAS DEFERENS ISOLATED FROM GUINEA-PIGS
- INFLUENCE OF POTASSIUM IONS ON CONTRACTION OF THE VAS DEFERENS ISOLATED FROM GUINEA-PIG
- INFLUENCE OF TRIMETAZIDINE ON THE INOTROPIC ACTION OF STROPHANTHIN-G ON GUINEA-PIG ATRIA IN ABNORMAL ION ENVIRONMENTS
- INFLUENCE OF CALCIUM AND SODIUM IONS ON POTASSIUM INDUCED CONTRACTION IN ISOLATED GUINEA-PIG VAS DEFERENS KEPT IN SUCROSE MEDIUM
- THE INFLUENCE OF THIAMINE TETRAHYDROFURFURYLDISULFIDE AGAINST STROPHANTHIN-G TOXICITY IN GUINEA-PIG ATRIA
- INCREASE IN Ca^ (Mg^)-ATPase ACTIVITY INDUCED BY A MOLSIDOMINE DERIVATIVE (SIN-1A) AND NITROGLYCERIN IN MICROSOMAL FRACTION OF GUINEA-PIG THORACIC AORTA
- THE ACTIONS OF TRIMETAZIDINE ON ISOLATED GUINEA-PIG ATRIA
- Involvement of Nicotinic Receptors in the Dorsal Motor Nucleus of the Vagus in Regulation of Gastric Motility in Rats.
- Central inhibition of gastric motility by intravenously administered nicotine in rats.
- PHARMACOLOGICAL STUDIES ON FIBRILLATION VOLTAGES IN DENERVATED SKELETAL MUSCLE OF RABBIT
- Effect of d-nicotine on the l-nicotine-induced increase in gastric acid secretion in rats.