Screening of Cell-Adhesive Peptide from the Human Laminin-5 α3 Chain Globular 2 and 3 Domains

スポンサーリンク

概要

• 論文の詳細を見る

• Laminin (LN)-5 is an epithelial specific adhesion component and a main ligand for keratinocyte. It regulates various cellular functions, including cell adhesion, spreading, and motility. The human LN-5 α3 chain globular (LG) 2 and 3 domains interact with integrin α3β1 selectively. Using peptide array-based interaction assay, screening of cell-adhesive peptide was performed with 6-mer peptide library of LG-2 and -3 domains. Eight peptides with high cell-adhesive effects were found, and the activity of DWKLVR (LN1143–1148) and GLRLLI (LN1239–1244) peptides showed about 2.5-fold increase compared to no peptide. From the adhesion inhibition assay, NFEGCI (LN1271–1276) and NQLLQD (LN1333–1338) peptides were seen to interact with integrin α3β1.

• 社団法人 化学工学会の論文
• 2008-03-01

著者

• Honda Hiroyuki

  Department of Biotechnology, School of Engineering, Nagoya University

• 本多 裕之

  名大院・工・生物機能

• Okochi Mina

  Department of Biotechnology, School of Engineering, Nagoya University

• Kato Ryuji

  Department of Biotechnology, School of Engineering, Nagoya University

• 本多 裕之

  名大院工・生物機能

• Kato Ryuji

  Department Of Biotechnology Graduate School Of Engineering Nagoya University

• 本多 裕之

  Department Of Biotechnology Graduate School Of Engineering Nagoya University:mext Innovative Researc

• Kato Ryuji

  Department Of Biotechnology School Of Engineering Nagoya University

• 本多 裕之

  Department Of Biotechnology School Of Engineering Nagoya University

• KAGA Chiaki

  Department of Biotechnology, School of Engineering, Nagoya University

• NOMURA Shigeyuki

  Department of Biotechnology, School of Engineering, Nagoya University

• Honda Hiroyuki

  Department Of Bioengineering Tokyo Institute Of Technology

• Honda Hiroyuki

  Department Of Biotechnology Graduate School Of Engineering Nagoya University

• Kaga Chiaki

  Department Of Biotechnology School Of Engineering Nagoya University

• Okochi Mina

  Department Of Biotechnology School Of Engineering Nagoya University

• Hosokawa Hiroyuki

  Department Of Biotechnology Graduate School Of Engineering Nagoya University:mext Innovative Researc

• Honda Hiroyuki

  Graduate School Of Engineering Nagoya University

• Honda Hiroyuki

  Department Of Chemical Engineering Faculty Of Engineering Nagoya University

• Nomura Shigeyuki

  Department Of Biotechnology School Of Engineering Nagoya University

• Kato Ryuji

  名古屋大学 工学研究科バイオテクノロジー講座

• Okochi Mina

  Department Of Biotechnology Nagoya University

• Hamada Hirobumi

  Department Of Biotechnology School Of Engineering Nagoya University

• Honda Hiroyuki

  Department Of Anesthesia Niigata City General Hospital

• Okochi Mina

  Department Of Biotechnology Graduate School Of Engineering Nagoya University

関連論文

• Droplet-based gene expression analysis using a device with magnetic force-based-droplet-handling system(METHODS)
• Scale-up fermentation of echinocandin type antibiotic FR901379(BIOCHEMICAL ENGINEERING)
• Improvement of FR901379 production by mutant selection and medium optimization(BIOCHEMICAL ENGINEERING)
• Directed evolution of angiotensin II-inhibiting peptides using a microbead display(METHODS)
• Magnetic manipulation device for the optimization of cell processing conditions(MEDICAL BIOTECHNOLOGY)
• Practical cell labeling with magnetite cationic liposomes for cell manipulation(METHODS)
• Effect of Global Transcriptional Regulators Related to Carbohydrate Metabolism on Organic Solvent Tolerance in Escherichia coli(BIOCHEMICAL ENGINEERING)
• Production of Recombinant Chicken IgY-Fc and Evaluation of Its Transport Ability into Avian Egg Yolks
• Directed evolution of angiotensin II-inhibiting peptides using a microbead display
• AN-P24 Magnetic manipulation device for the optimization of cell processing(Section I Animal and Plant Cell Cultures)
• Screening of Epithelial Cell-Adhesive Peptides from Fibronectin Loop Region and Its Cell Specificity
• A Motif Detection and Classification Method for Peptide Sequences Using Genetic Programming(BIOINFORMATICS)
• Mag-Seeding of Rat Bone Marrow Stromal Cells into Porous Hydroxyapatite Scaffolds for Bone Tissue Engineering(CELL AND TISSUE ENGINEERING)
• Effective Cell-Seeding Technique Using Magnetite Nanoparticles and Magnetic Force onto Decellularized Blood Vessels for Vascular Tissue Engineering(CELL AND TISSUE ENGINEERING)
• Gene Expression Property of High-Density Three-Dimensional Tissue of HepG2 Cells Formed in Radial-Flow Bioreactor(BIOINFORMATICS)
• Three-Dimensional High-Density Culture of HepG2 Cells in a 5-ml Radial-Flow Bioreactor for Construction of Artificial Liver(Biochemical Engineering)
• Targeting Hyperthermia for Renal Cell Carcinoma Using Human MN Antigenspecific Magnetoliposomes
• Cancer DNA Microarray Analysis Considering Multi-subclass with Graph-based Clustering Method(BIOINFORMATICS)
• Identification of HLA-A24-Restricted Epitopes with High Affinities to Hsp70 Using Peptide Arrays(METHODS)
• Screening of Cell-Adhesive Peptide from the Human Laminin-5 α3 Chain Globular 2 and 3 Domains
• Screening of Anti-Tumor Peptide Vaccines with High Affinity to Hsp70 Using Peptide Array
• Peptide Informatics - Novel Method for Screening and Design of Biologically Active Peptides
• Peptide Array-Based Interaction Assay of Solid-Bound Peptides and Anchorage-Dependant Cells and Its Effectiveness in Cell-Adhesive Peptide Design (BIOINFORMATICS)
• Hidden Markov Model-Based Prediction of Antigenic Peptides That Interact with MHC Class II Molecules
• Drastic change in cell surface hydrophobicity of a new bacterial strain, Pseudomonas sp. TIS1-127, induced by growth temperature and its effects on the toluene-conversion rate(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
• Prediction of Peptide Binding to Major Histocompatibility Complex Class II Molecules through Use of Boosted Fuzzy Classifier with SWEEP Operator Method(BIOINFORMATICS)
• Expression of a Thermostable Cellulase Gene from a Thermophilic Anaerobe in Saccharomyces cerevisiae
• Production of Ethanol in Repeated-Batch Fermentation with Membrane-Type Bioreactor
• Diversity of Cellulases Produced by a Thermophilic Anaerobe Strain NA10
• Molecular Cloning of Ruminococcus albus Cellulase Gene(Biological Chemistry)
• Incorporation of Capillary-Like Structures into Dermal Cell Sheets Constructed by Magnetic Force-Based Tissue Engineering
• Application of Ultra-Water-Repellent Surface to Cell Culture(CELL AND TISSUE ENGINEERING)
• Heat Immunotherapy Using Magnetic Nanoparticles and Dendritic Cells for T-Lymphoma(MEDICAL BIOTECHNOLOGY, Advances in Biomedical Science and Engineering)
• Screening of Cytokines to Enhance Vaccine Effects of Heat Shock Protein 70-Rich Tumor Cell Lysate(MEDICAL BIOTECHNOLOGY, Advances in Biomedical Science and Engineering)
• Medical Application of Functionalized Magnetic Nanoparticles(Advances in Biomedical Science and Engineering)
• Complete Regression of Mouse Mammary Carcinoma with a Size Greater than 15 mm by Frequent Repeated Hyperthermia Using Magnetite Nanoparticles
• Selective hyperthermia using magnetoliposomes to target cervical lymph node metastasis in a rabbit tongue tumor model
• Proliferation and Stratification of Keratinocyte on Cultured Amniotic Epithelial Cells for Tissue Engineering(MEDICAL BIOTECHNOLOGY)
• Tumor regression by combined immunotherapy and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanoma
• Transglutaminase-Mediated Gelatin Matrices Incorporating Cell Adhesion Factors as a Biomaterial for Tissue Engineering
• Radiation-Inducible TNF-α Gene Expression under Stress-Inducible Promoter gadd 153 for Cancer Therapy
• Bystander-Killing Effect and Cyclic Induction of TNF-α Gene under Heat-Inducible Promoter gadd 153
• Colominic Acid Production from Escherichia coli in a Fed-Batch Culture under the Control of Ammonium Ions Using an FIA System
• Effective Lactic Acid Production by Two-Stage Extractive Fermentation
• Time-Course Data Analysis of Gene Expression Profiles Reveals purR Regulon Concerns in Organic Solvent Tolerance in Escherichia coli(Microbial Physiology and Biotechnology)
• SELECTION CRITERIA OF OXYGEN CARRIERS UTILIZABLE FOR AUTOTROPHIC GROWTH IMPROVEMENT OF ALCALIGENES EUTROPHUS UNDER LOWERED OXYGEN PARTIAL PRESSURE
• ANALYSIS OF OXYGEN TRANSFER ENHANCEMENT BY OXYGEN CARRIER IN THE AUTOTROPHIC CULTIVATION OF ALCALIGENES EUTROPHUS UNDER LOW OXYGEN PARTIAL PRESSURE
• PHYTOHORMONE CONTROL FOR PLANT CELL CULTURE USING A BIOREACTOR EQUIPPED WITH IN-LINE FEEDING COLUMN
• A MODEL ANALYSIS OF MICROBIAL RETAINMENT PROCESS IN POROUS SUPPORT PARTICLES IN A FLUIDIZED-BED WASTEWATER TREATMENT REACTOR
• Preparation of L929 Cell Array by Magnetic Pin Holder Device for Single Cell Function Analysis
• OVERPRODUCTION OF FOREIGN GENE PRODUCT IN RECOMBINANT ESCHERICHIA COLI BY IN SITU ADSORPTION OF TRYPTOPHAN
• 4-S-Cysteaminylphenol-loaded magnetite cationic liposomes for combination therapy of hyperthermia with chemotherapy against malignant melanoma
• Prognostic models in patients with non-small-cell lung cancer using artificial neural networks in comparison with logistic regression
• Proposal of Pumpless, Valveless, and Flowless Miniaturized Reactor Using Magnetic Beads for the Portable Analysis Device
• Fabrication of Antigen Sensors Using Carbon Nanotube Field Effect Transistors
• Preparation of Tumor-Specific Magnetoliposomes and Their Application for Hyperthermia
• Fabrication of vertically-aligned CNT electrodes using plasma-enhanced CVD for chemical sensors
• Modeling of Consumers' Preferences for Regular Coffee Samples and Its Application to Product Design
• Determination of the Blending Ratio of Regular Coffee Samples by Information Technology
• Multiple fuzzy neural network system for outcome prediction and classification of 220 lymphoma patients on the basis of molecular profiling
• Selection of Causal Gene Sets for Lymphoma Prognostication from Expression Profiling and Construction of Prognostic Fuzzy Neural Network Models(MEDICAL BIOTECHNOLOGY)
• Fuzzy Neural Network Applied to Gene Expression Profiling for Predicting the Prognosis of Diffuse Large B-cell Lymphoma
• Inference of Common Genetic Network Using Fuzzy Adaptive Resonance Theory Associated Matrix Method(BIOINFORMATICS)
• Artificial Neural Network Predictive Model for Allergic Disease Using Single Nucleotide Polymorphisms Data
• Determination of Operating Conditions in Activated Sludge Process Using Fuzzy Neural Network and Genetic Algorithm
• Construction of COD Simulation Model for Activated Sludge Process by Recursive Fuzzy Neural Network
• Construction of COD Simulation Model for-Acivated Sludge Process by Fuzzy Neural Network
• Magnetic Characterization of Magnetite Particles for MR Contrast Agents
• A Preprocessing Method for Inferring Genetic Interaction from Gene Expression Data Using Boolean Algorithm(BIOINFORMATICS)
• Prognostic Predictor with Multiple Fuzzy Neural Models Using Expression Profiles from DNA Microarray for Metastases of Breast Cancer(BIOINFORMATICS)
• Proposal of Reliability Index in Search for Reliable Solutions of Reverse Calculation Based on Fuzzy Neural Network Modeling
• Evaluation of the Alzheimer-Type Dementia by Magnetic Resonance Imaging Using Fuzzy Neural Networks
• Simple and Rapid Cell Growth Assay Using Tetrazolium Violet Coloring Method for Screening of Organic Solvent Tolerant Bacteria
• Construction of an Electroencephalogram-Based Brain-Computer Interface Using an Artificial Neural Network(Welfare Engineering)
• Analysis of Organic Solvent Tolerance in Escherichia coli Using Gene Expression Profiles from DNA Microarrays
• A New Reliable Cancer Diagnosis Method Using Boosted Fuzzy Classifier with a SWEEP Operator Method
• Association Study between Apolipoprotein L and Schizophrenia by Exhaustive and Rule-Based Combination Analysis for Identification of Multilocus Interactions(BIOINFORMATICS)
• Proposal of New Gene Filtering Method, BagPART, for Gene Expression Analysis with Small Sample(BIOINFORMATICS)
• Classification of Intramural Metastases and Lymph Node Metastases of Esophageal Cancer from Gene Expression Based on Boosting and Projective Adaptive Resonance Theory(BIOINFORMATICS)
• Classification Method for Predicting the Development of Myocardial Infarction by Using the Interaction between Genetic and Environmental Factors
• Prediction of Occurrence of Heterocapsa circularisquama Red Tide by Means of Fuzzy Neural Network
• Human Antithrombin III variant Production from Recombinant BHK Cells in a Fed-Batch Culture with On-Line Control of Glucose and Glutamine Concentrations
• Performance of a Shaking Vessel-Type Bioreactor with a Current Pole
• Lymphoma Prognostication from Expression Profiling Using a Combination Method of Boosting and Projective Adaptive Resonance Theory
• Development of Rotating-Mesh Basket Type Bioreactor for Carrot Embryo Production in Immobilized Callus System
• Characterization on Heat Sterilization of a Novel Autoclave with a Turntable for Rotation
• Fuzzy Neural Network-Based Prediction of the Motif for MHC Class II Binding Peptides
• Enhanced Anthocyanin Production from Grape Callus in an Air-Lift Type Bioreactor Using a Viscous Additive-Supplemented Medium
• Enhanced and Prolonged Production of Plantlets Regenerated from Carrot Callus in a Viscous Additive-Supplemented Medium
• Lipase Production in Two-Step Fed-Batch Culture of Organic Solvent-Tolerant Pseudomonas aeruginosa LST-03
• Release of Embryogenic Carrot Cells with High Regeneration Protency from Immobilized Alginate Beads
• Prolonged loss of leg myogenic motor evoked potentials during thoracoabdominal aortic aneurysm repair, without postoperative paraplegia
• Development of Chitosan-Magnetite Aggregates Containing Nitrosomonas europaea Cells for Nitrification Enhancement
• PRODUCTION OF Fv FRAGMENT OF MONOCLONAL ANTIBODY FROM RECOMBINANT METHYLOTROPHIC YEAST, PICHIA PASTORIS
• Effective tPA Production by BHK Cells in Nutrients-Controlled Culture Using an On-Line HPLC Measuring System
• Enhancement of tPA Production under Hyperoxic Conditions by BHK Cells in Serum-Free and Serum-Containing Cultures
• Rapid Enzyme-Linked Immunosorbent Assay with Functional Magnetite Particles
• Development of Chitosan-Conjugated Magnetite for Magnetic Cell Separation
• Purification and Characterization of Recombinant Bovine Cathepsin C
• Effcient Production of Recombinant Bovine Cathepsin C by High Cell Density Culture of Methylotrophic Yeast Candida boidinii

もっと見る 閉じる

スポンサーリンク