Effect of Grifolan on the Ascites Form of Sarcoma 180(Biological)
スポンサーリンク
概要
- 論文の詳細を見る
The antitumor activity of a (1→3)-β-D-glucan, grifolan, which was obtained from a fungus, Grifola frondosa, on the ascites form of Sarcoma 180 in ICR mice was examined. Grifolan waseffective on the ascites tumor when it was administered before tumor transplantation (days-7-1) as a single dose of 2mg/mouse by i.p. injection, but administration after the tumortransplantation was ineffective. The antitumor activity was transferred to untreated mice byinjecting the peritoneal exudate cells obtained from grifolan-treated mice. The antitumor activity ofgrifolan was augmented by vaccination of mice with live sarcoma 180 cells(s.c. injection).
- 社団法人日本薬学会の論文
- 1987-06-25
著者
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大野 尚仁
Tokyo University of Pharmacy and Life Science (formerly Tokyo College of Pharmacy)
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宿前 利郎
Tokyo University of Pharmacy and Life Science (formerly Tokyo College of Pharmacy)
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宿前 利郎
東京薬科大学
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佐藤 吉朗
Nippon Beet Sugar Mfg. Co. Ltd.
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鈴木 良幸
Nippon Beet Sugar Mfg. Co. Ltd.
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大野 尚仁
東京薬科大学免疫学
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大野 尚仁
帝京大学 医学部微生物学講座
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及川 昭蔵
Nippon Beet Sugar Mfg. Co. Ltd.
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Ohno N
Lab. Immunopharmacolgy Of Microbial Products Tokyo University Of Pharmacy And Life Science School Of
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