Effect of Intraperitoneally Administered β-1,3-Glucan, SSG, Obtained from Sclerotinia sclerotiorum IFO 9395 on the Functions of Murine Alveolar Macrophages
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概要
- 論文の詳細を見る
The effect of intraperitoneally (i.p.) administered SSG, a β-1,3-glucan obtained from the culture filtrate of the fungus Sclerotinia sclerotiorum IFO 9395,on the functions of alveolar macrophages (AM) in CDF_1 mice was examined. SSG administered i.p. increased the number of AM and enhanced several functions of murine AM (lysosomal enzyme activity, phagocytic activity, candidacidal activity, H_2O_2 production and interleukin 1 (IL-1) production) at a dose of 250μg/mouse on days 1 and 8,especially on day 8. Furthermore, SSG(250μg/mouse)administered i.p. for 10 consecutive days significantly inhibited the experimental pulmonary metastasis of Lewis Lung Carcinoma (3LL) on BDF_1 mice.
- 社団法人日本薬学会の論文
- 1991-01-25
著者
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宿前 利郎
Tokyo University of Pharmacy and Life Science (formerly Tokyo College of Pharmacy)
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宿前 利郎
東京薬科大学 薬 免疫
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宿前 利郎
東京薬科大学
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櫻井 照明
Laboratory of Immunopharmacology of Microbial Products, Tokyo College of Pharmacy
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櫻井 照明
Laboratory Of Immunopharmacology Of Microbial Products Tokyo College Of Pharmacy
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桜井 照明
東京薬科大学 第1微生物
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及川 昭蔵
Nippon Beet Sugar Mfg. Co. Ltd.
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鈴木 巌
Tokyo College of Pharmacy
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櫻井 照明
Tokyo College of Pharmacy
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増田 昭芳
Nippon Beet Sugar Mfg., Co., Ltd.
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大沢 真澄
Nippon Beet Sugar Mfg., Co., Ltd.
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木下 晃
Tokyo College of Pharmacy
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鈴木 巖
Tokyo College of Pharmacy
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大沢 真澄
Nippon Beet Sugar Mfg. Co. Ltd.
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増田 昭芳
Nippon Beet Sugar Mfg. Co. Ltd.
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