The Protective Effect of BRAND'S Essence of Chicken (BEC) on Energy Metabolic Disorder in Mice Loaded with Restraint Stress
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概要
- 論文の詳細を見る
We investigated the effects of BRAND'S Essence of Chicken (BEC) on the basic metabolism of plasma lipids in mice loaded with restraint stress. When a lipid emulsion was intravenously injected into mice, 20 hr restraint stress prolonged the elimination of plasma triglyceride (TG). The results indicated that lipid metabolism was definitely disrupted by stress, and that the use of TG as an energy source decreased. The plasma TG level was 320±27mg/dl 35 min after Intralipid^[○!R] administration in restrained mice, while it was 253±23 mg/dl in the restrained mice that were given 5ml/kg of BEC. The improved plasma lipid metabolism was well explained by the finding that lipoprotein lipase in omental adipose tissue was remarkably improved by BEC. Our study shows that BEC improves metabolic dysfunction possibly by utilizing plasma lipids as energy sources and elevating lipoprotein lipase activity reduced by stress. The anti-stress effect of BEC may partly be related to improved plasma lipid metabolism for energy utilization.
- 公益社団法人日本薬学会の論文
- 2006-02-01
著者
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KISO Yoshinobu
Institute for Health Care Science, Suntory Ltd.
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Shibata Hiroko
Laboratory Of Pharmaceutical Proteomics National Institute Of Biomedical Innovation (nibio)
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Shibata Hiroko
医薬基盤研究所 創薬プロテオミクスプロジェクト
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SHIBATA Hiroshi
Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd.
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Yao Xin-sheng
Medical College Jinan University
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Yao Xin
Medical College Jinan University
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Yao Xin-sheng
Institute Of Traditional Chinese Medicine And Natural Products Jinan University
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深見 治一
Institute For Biomedical Research Research Center Suntory Ltd.
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深見 治一
サントリー(株)基礎研
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Yao Xin-sheng
Institute Of Molecular Immunology Southern Medical University
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Kiso Yoshinobu
Laboratory For Health Care Science Research Center Suntory Ltd.
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Kiso Yoshinobu
Institute For Biomedical Research Suntory Ltd.
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Tsuruoka N
Laboratory For Health Care Science Research Center Suntory Ltd.
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KURIHARA Hiroshi
Institute of Traditional Chinese Medicine & Natural Products, Jinan University
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Yao Xin-sheng
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University:shenzhen Research C
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Nagai Hajime
Brand's Centre For Health And Nutritional Sciences
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Kiso Yoshinobu
Suntory Ltd. Osaka Jpn
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Shibata Hiroshi
Laboratory For Health Care Science Research Center Suntory Ltd.
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Kawanishi Hideaki
Institute For Health Care Science Suntory Ltd.
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Shibata H
Laboratory For Health Care Science Research Center Suntory Ltd.
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Tsuruoka Nobuo
Institute for Health Care Science, Research Center, Suntory Ltd.
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Fukami Harukazu
Institute for Health Care Science, Technological Development Center, Suntory Ltd.
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Yao X‐s
Inst. Of Traditional Chinese Medicine And Natural Products Jinan Univ.
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Fukami Harukazu
Department Of Bioscience And Biotechnology Faculty Of Bioenvironmental Science Kyotogakuen Universit
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Fukami Harukazu
Dep. Of Bioscience And Biotechnology Fac. Of Bioenvironmental Sci. Kyotogakuen Univ.
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Fukami Harukazu
Institute For Health Care Science Technological Development Center Suntory Ltd.
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Yao X‐s
Coll. Of Traditional Chinese Materia Medica Shenyang Pharmaceutical Univ.
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Kurihara H
Institute Of Traditional Chinese Medicine And Natural Products Jinan University
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Tsuruoka Nobuo
Institute For Health Care Science Suntory Limited
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Kajimoto Yoshinaga
Institute For Health Care Science Suntory Ltd.
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Kitagawa Yoshinori
Institute For Health Care Science Suntory Wellness Limited
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Fukami Harukazu
Department Of Bioscience And Biotechnology Faculty Of Bioenvironmental Science Kyotogakuen Universit
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Saito Hiroyuki
Third Department Of Internal Medicine Asahikawa Medical College
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Shibata Hiroshi
Institute Of Health Care Science Suntory Wellness Limited
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Shibata Hiroshi
Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.:department Of Animal Scienc
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SHIBATA Hiroshi
Institute for Biomedical Research, Suntory Limited
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