Coumarins from Campylotropis hirtella (FRANCH.) SCHINDL. and Their Inhibitory Activity on Prostate Specific Antigen Secreted from LNCaP Cells
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概要
- 論文の詳細を見る
Campylotropis hirtella (FRANCH.) SCHINDL. was used as a folk medicine for the treatment of benign prostate hyperplasia (BPH) in China. In this study, two new coumarins, 7,2',4'-trihydroxy-5-methoxy-3-arylcoumarin (1), 6-[(1S,2S*)-2-angeloyloxy-1,3-dihydroxy-3-methylbutyl]-7-methoxycoumarin, named angelol M (2), together with eleven known related compounds (3-13) were isolated from this plant under the bioassay guided fractionation. All the compounds showed activity with different levels in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells, using ELISA method.
- 公益社団法人日本薬学会の論文
- 2008-09-01
著者
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Han Hui-ying
Cancer Biology Group Department Of Anatomy Faculty Of Medicine The University Of Hong Kong
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Yao Xin-sheng
Medical College Jinan University
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Yao Xin
Medical College Jinan University
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Liu Hong-wei
Capital Medical University School Of Chemical Biology And Pharmaceutical Sciences
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Yao Xin-sheng
Inst. Of Traditional Chinese Medicine And Natural Products Jinan Univ.
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Yao Xin-sheng
School Of Traditional Chinese Materia Medicine Shengyang Pharmaceutical Univ.
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Yao Xin-sheng
Institute Of Traditional Chinese Medicine And Natural Products Jinan University
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Wang Nai-li
Dep. Of Natural Products Chemistry Shenyang Pharmaceutical Univ.
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Wang Nai-li
Key Laboratory For Research & Development Of New Drugs From Traditional Chinese Medicine & N
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Yao Xin-sheng
Institute Of Molecular Immunology Southern Medical University
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Yao Xin-sheng
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University:shenzhen Research C
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WEN Ping
College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
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Wen Ping
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University
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Yao X‐s
Inst. Of Traditional Chinese Medicine And Natural Products Jinan Univ.
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Wang Nai-li
Key Lab For New Drugs Res. Of Traditional Chinese Medicine Shenzhen Res. Inst. Of Tsinghua Univ.
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