New Stilbenoids from Pholidota yunnanensis and Their Inhibitory Effects on Nitric Oxide Production
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概要
- 論文の詳細を見る
Six new stilbenoids, a (bibenzyldihydrophenanthrene) ether designated phoyunnanin D (1), a bis (dihydrophenanthrene) ether designated phoyunnanin E (2), and four stilbenes designated phoyunbene A-D (3-6), were isolated from the air-dried whole plant of Pholidota yunnanensis ROLFE. The new compounds were identified as 7-[2-(3-hydroxyphenethyl)-4-hydroxy-6-methoxyphenoxy]-4-hydroxy-2-methoxy-9, 10-dihydrophenanthrene (1), 1-[(9, 10-dihydro-4-hydroxy-2-methoxy-7-phenanthrenyl) oxy]-4, 7-dihydroxy-2-methoxy-9, 10-dihydrophenanthrene (2), trans-3, 3'-dihydroxy-2', 4', 5-trimethoxystilbene (3), trans-3, 4'-dihydroxy-2', 3', 5-trimethoxystilbene (4), trans-3, 3'-dihydroxy-2', 5-dimethoxystilbene (5), and trans-3-hydroxy-2', 3', 5-trimethoxys-tilbene (6) based on spectroscopic evidence. Furthermore, the inhibitory effects of compounds 1-6 on nitric oxide production in a murine macrophage-like cell line (RAW 264.7) activated by lipopolysaccharide and interferon-γ were examined.
- 公益社団法人日本薬学会の論文
- 2006-01-01
著者
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Yao Xin-sheng
Medical College Jinan University
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Yao Xin
Medical College Jinan University
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Yao Xin-sheng
College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
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Liu Hong-wei
Capital Medical University School Of Chemical Biology And Pharmaceutical Sciences
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Yao Xin-sheng
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University
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Wang Nai-li
Dep. Of Natural Products Chemistry Shenyang Pharmaceutical Univ.
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Yao Xin-sheng
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University:shenzhen Research C
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Wang Nai-li
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University:shenzhen Research C
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KITANAKA Susumu
Department of Pharmacognosy, College of Pharmacy, Nihon University
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Kitanaka Susumu
Res. Unit Of Pharmacognosy School Of Pharmacy Nihon Univ.
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Kitanaka Susumu
Department Of Pharmacognosy College Of Pharmacy Nihon University
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Wang Jue
Department Of Pharmacognosy College Of Pharmacy Nihon University
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Yao X‐s
Inst. Of Traditional Chinese Medicine And Natural Products Jinan Univ.
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Guo Xiao-Yu
College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
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LIU Hong-Wei
Shenzhen Research Center of Traditional Chinese Medicines and Natural Products, Tsinghua Campus, Uni
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Yao X‐s
Coll. Of Traditional Chinese Materia Medica Shenyang Pharmaceutical Univ.
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Wang Nai-li
Key Lab For New Drugs Res. Of Traditional Chinese Medicine Shenzhen Res. Inst. Of Tsinghua Univ.
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Guo Xiao-yu
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University
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WANG Jue
Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
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