Copacamphane, Picrotoxane and Cyclocopacamphane Sesquiterpenes from Dendrobium nobile
スポンサーリンク
概要
- 論文の詳細を見る
Dendronobilins K-N, four new sesquiterpenes with copacamphane-type (1), picrotoxane-type (2,3) and cyclocopacamphane-type (4) skeletons, were isolated from the n-BuOH soluble fraction of the 60% ethanol extract of the steins of Dendrobium nobile. Their structures were established as 2β,11,12-trihydroxycopacamphan-15-one (1), (2β,3β,4β,5β)-2,4,11,12-tetrahydroxypicrotoxan-3(15)-olactone (2), (2β,3β,5β)-2,11,12,13-tetrahydroxypicrotoxan-3(15)-olactone (3), and (5β,8β)-cyclocopacamphane-5,8,12,15-tetrol (4) on the basis of spectroscopic analysis. Compounds 3 and 4 were inactive in both immunomodulatory and antioxidant bioassay in vitro.
- 公益社団法人日本薬学会の論文
- 2008-06-01
著者
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Wang Zhao
Medical School Tsinghua University
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Yao Xin-sheng
College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
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Yao Xin-sheng
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University
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Zhang Xue
College Of Traditional Chinese Medicine Shenyang Pharmaceutical University
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Zhang Xue
Key Laboratory For Research & Development Of New Drugs From Traditional Chinese Medicine & N
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Tu Feng-juan
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University
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Wang Nai-li
Key Laboratory For Research & Development Of New Drugs From Traditional Chinese Medicine & N
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YU Hai-Yang
College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
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Yu Hai-yang
College Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University
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Wang Nai-li
Key Lab For New Drugs Res. Of Traditional Chinese Medicine Shenzhen Res. Inst. Of Tsinghua Univ.
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