Triterpenoids from Hippophae rhamnoides L. and Their Nitric Oxide Production-Inhibitory and DPPH Radical-Scavenging Activities
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概要
- 論文の詳細を見る
In our investigation on the chemical constituents of Hippophae rhamnoides L., the chloroform-soluble fraction of the 80% acetone extract of branch bark was observed to inhibit nitric oxide (NO) production in a lipopolysaccharide and recombinant mouse interferon-γ-activated murine macrophage-like cell line, RAW 264.7 cells. Two new triterpenoids, 2-O-trans-p-coumaroyl maslinic acid (1) and 2-O-caffeoyl maslinic acid (2), and three known triterpenoids, oleanolic acid (3), 3-O-trans-p-coumaroyl oleanolic acid (4), and 3-O-caffeoyl oleanolic acid (5), and 6-methoxy-2H-1-benzopyran (6) and β-sitosterol (7) were isolated from the branch bark extract. Their inhibitory activities on the production of NO in RAW 264.7 cells and radical-scavenging activities were examined.
- 公益社団法人日本薬学会の論文
- 2007-01-01
著者
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LI He-Ran
College of Pharmacy, Nihon University
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KITANAKA Susumu
College of Pharmacy, Nihon University
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Kitanaka Susumu
Res. Unit Of Pharmacognosy School Of Pharmacy Nihon Univ.
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Kitanaka Susumu
College Of Pharmacy Nihon University
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WANG Jue
College of Pharmacy, Nihon University
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Wang Jue
College Of Pharmacy Nihon University
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DAIKONYA Akihiro
College of Pharmacy, Nihon University
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Yang Zhi-gang
China National Administration Center For Seabuckthorn Development Ministry Of Water Resources:colleg
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Lu Shun-guang
China National Administration Center For Seabuckthorn Development Ministry Of Water Resources
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Wang Li-yan
College Of Pharmacy Nihon University
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LI Yong-Hai
China National Administration Center for Seabuckthorn Development, Ministry of Water Resources
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WEN Xiu-Feng
China National Administration Center for Seabuckthorn Development, Ministry of Water Resources
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Daikonya Akihiro
Res. Unit Of Pharmacognosy School Of Pharmacy Nihon Univ.
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Daikonya Akihiro
College Of Pharmacy Nihon University
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Li Yong-hai
China National Administration Center For Seabuckthorn Development Ministry Of Water Resources
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Wen Xiu-feng
China National Administration Center For Seabuckthorn Development Ministry Of Water Resources
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