Cytotoxic Cardenolides from Woods of Euonymus alata
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概要
- 論文の詳細を見る
Three cytotoxic cardenolides, acovenosigenin A 3-O-α-L-ramnopyranoside (1), euonymoside A (2) and euonymusoside A (3), were isolated from the woods of Euonymus alata (Celastraceae). The chemical structure of a new cardenolide, euonymusoside A (3) has been elucidated on the basis of extensive spectral analysis and enzymic hydrolysis to be acovenosigenin A (1β, 3β, 14β-trihydroxy-5β-cardenolide) 3-O-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl(1→4)-α-L-rhamnopyranoside. All three showed potent cytotoxic activity against some neoplastic cell lines.
- 公益社団法人日本薬学会の論文
- 1996-03-15
著者
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KITANAKA Susumu
College of Pharmacy, Nihon University
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Mizoue K
Taisho Pharmaceutical Co. Ltd. Saitama Jpn
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Mizoue Kazutoshi
Taisho Pharmaceutical Co. Ltd.
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TAKIDO Michio
College of Pharmacy, Nihon University
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Kitanaka Susumu
College Of Pharmacy Nihon University
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Takido M
College Of Pharmacy Nihon University
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Takido Michio
College Of Pharmacy Nihon University
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Nakaike S
Taisho Pharmaceutical Co. Ltd. Saitama Jpn
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NAKAIKE Shiro
Taisho Pharmaceutical Co., Ltd.,
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Mizoue Kazutoshi
Taisho Pharmaceutical Co. Ltd
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