Bioactive Phenolic Compounds from Catharanthus roseus and Vinca minor
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概要
- 論文の詳細を見る
Kaempferol 3-O-α-L-rhamnopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside (mauritianin), quercetin 3-O-α-L-rhamnopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside and chlorogenic acid were isolated from the leaves of Catharanthus roseus (L.) G. DON (=Vinca rosea L.), used as the herbal medicine "Herba Catharanthi." Kaempferol 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside-7-O-β-D-glucopyranoside, 2,3-dihydroxybenzoic acid, 3-β-D-glucopyranosyloxy-2-hydroxybenzoic acid (vincoside) and chlorogenic acid were isolated from the leaves of Vinca minor L,, used as the herbal medicine "Periwinkles." Mauritianin enhanced the 12-O-tetradecanoylphorbol-13-acetate-suppressed delayed-type hypersensitivity in mice, indicating that mauritianin may augment the immune resistance to cancer. 2,3-Dihydroxybenzoic acid showed a potent radical-scavenging activity, which may lower the risk of cancer. 2,3-Dihydroxybenzoic acid prevented the formation of advanced glycation end products (AGEs), which may reduce development of diabetic complications.
- 日本生薬学会の論文
- 1996-12-20
著者
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Tanaka T
Gifu Pharmaceutical University
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Hirota Akira
School Of Food And Nutritional Sciences Univ. Of Shizuoka
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Hirota Akira
School Of Food And Nutritional Sciences University Of Shizuoka
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Yasukawa Ken
College Of Pharmacy Nihon University
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Takido Michio
College Of Pharmacy Nihon University
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Nishibe Sansei
Faculty Of Pharmaceutical Sciences Health Science University Of Hokkaido
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Morimitsu Yasujiro
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka:la
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KAWAMURA TOMOKO
Faculty of Pharmacy, Meijo University
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Takenaka Takako
Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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FUJIKAWA Takahiko
Faculty of Medicine, Mie University
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NORO YUKIO
Faculty of Pharmacy, Meijo University
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Nishibe Sansei
北海道医療大学 薬
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FUJIKAWA TAKAHIRO
Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido
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MORIMITSU YASUJIRO
School of Food and Nutritional Sciences, University of Shizuoka
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Noro Yukio
Faculty Of Pharmacy Meijo University
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Morimitsu Yasujiro
School Of Food And Nutritional Sciences University Of Shizuoka
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Kawamura Tomoko
Faculty Of Pharmacy Meijo University
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Fujikawa Takahiro
Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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Tanaka Toshihiro
Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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