Studies on the 1,1-Diphenyl-2-picrylhydrazyl Radical Scavenging Mechanism for a 2-Pyrone Compound
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概要
- 論文の詳細を見る
The radical scavenging mechanisms for the 2-pyrone compound, 4-hydroxy-3,6-dimethyl-2H-pyrane-2-one (1), and the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (4) in several solvent systems were evaluated by the quantitative change in compounds detected at 270 nm and subsequent HPLC analyses. The HPLC profile for each condition suggested that the reaction proceeded by a different mechanism in each solvent system. In organic solvents (CHCl_3,iso-propanol, and EtOH), 1-[4-(3,4-dihydro-3,6-dimethyl-2,4-dioxo-2H-pyran-3-yl) phenyl]-1-phenyl-2-picrylhydrazine (2) was produced as an adduct of the DPPH radical and 1. On the other hand, the reaction in a buffer solution (an acetate buffer at pH 5.5) gave several degradation products with 1-[4-(2,3-dihydro-2,5-dimethyl-3-oxo-fur-2-yl) phenyl]-1-phenyl-2-picrylhydrazine (5), this being structurally elucidated by spectroscopic analyses. The decrease of the DPPH radical in each reaction system suggests that compound 1 could scavenge about 1.5-1.8 equivalents of the radical in organic solvents and about 3.5-3.9 in the buffer solution.
- 社団法人日本農芸化学会の論文
- 2000-02-23
著者
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ABE Naoki
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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HIROTA Akira
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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Abe N
Faculty Of Applied Bio-science Tokyo University Of Agriculture
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Abe Naoki
School Of Food And Nutritional Sciences University Of Shizuoka:(present Address)department Of Nutrit
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Hirota Akira
School Of Food And Nutritional Sciences Univ. Of Shizuoka
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Hirota A
Department Of Agricultural Chemistry University Of Osaka Prefecture
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Hirota Akira
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Hirota Akira
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Tsuchiya Yukiko
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Nemoto Atsuko
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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NEMOTO Aya
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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HOJO Hiroshi
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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Abe N
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Abe Naoki
School Of Food And Nutritional Sciences University Of Shizuoka
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Hojo H
Department Of Applied Biochemistry Institute Of Glycoscience Tokai University
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Hojo Hiroshi
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Abe Naoki
Laboratory Of Applied Microbiology Department Of Microbial Biotechnology Graduate School Of Agricult
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