Synthesis of an Unnatural N-Glycan-linked Dolichyl Pyrophosphate Precursor(Organic Chemistry)

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概要

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• An unnatural α-D-mannopyranose-linked chitobiosyl dolichyl pyrophosphate, a stereoisomer of the N-glycan biosynthesis intermediate, was synthesized. The protected trisaccharide, α-D-Man- (1→4) -β-D-GlcNAc- (1→4) -D-GlcNAc, carrying a 4-methylbenzoyI group was prepared for the convenience of a TLC analysis. 1-O-Phosphorylation, condensation with dolichyl phosphate, and subsequent deprotection afforded the title compound.

• 社団法人日本農芸化学会の論文
• 2003-08-23

著者

• HOJO Hironobu

  Institute for Protein Research, Osaka University

• NAKAHARA Yoshiaki

  Institute of Glycotechnology, Department of Applied Biochemistry, Tokai University

• Hojo Hironobu

  Institute For Protein Research Osaka University

• NAKAHARA Yuko

  Institute of Glycotechnology, Department of Applied Biochemistry, Tokai University

• NONAKA Tomoharu

  Institute of Glycotechnology, Department of Applied Biochemistry, Tokai University

• Nakahara Y

  Department Of Applied Biochemistry Institute Of Glycoscience Tokai University

• Hojo H

  Department Of Applied Biochemistry Institute Of Glycoscience Tokai University

• Nonaka Tomoharu

  Institute Of Glycotechnology Department Of Applied Biochemistry Tokai University

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