Novel Lipoxygenase Inhibitors, Tetrapetalone B, C, and D from Streptomyces sp
スポンサーリンク
概要
- 論文の詳細を見る
Three novel lipoxygenase inhibitors, tetrapetalone B (2, C28H35NO9), C (3, C26H34NO8), and D (4, C28H36NO10), were isolated from a culture broth of Streptomyces sp. USF-4727 that produced a lipoxygenase inhibitor tetrapetalone A (1) simultaneously. Each chemical structure was revealed by spectroscopic evidence, this suggests that these three compounds are structurally related to 1. They had a tetracyclic skeleton and a β-D-rhodinosyl moiety. Tetrapetalone B, C, and D inhibited soybean lipoxygenase with IC50: 320, 360, and 340 μM respectively.
- 2004-04-23
著者
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KOMODA Toshikazu
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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KISHI Madoka
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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ABE Naoki
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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SUGIYAMA Yasumasa
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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HIROTA Akira
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
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Abe N
Faculty Of Applied Bio-science Tokyo University Of Agriculture
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Abe Naoki
School Of Food And Nutritional Sciences University Of Shizuoka:(present Address)department Of Nutrit
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Kishi Madoka
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Hirota Akira
School Of Food And Nutritional Sciences Univ. Of Shizuoka
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Hirota A
Department Of Agricultural Chemistry University Of Osaka Prefecture
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Hirota Akira
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Hirota Akira
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Komoda Toshikazu
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Sugiyama Yasumasa
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Abe N
Laboratory Of Applied Microbiology School Of Food And Nutritional Sciences University Of Shizuoka
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Abe Naoki
School Of Food And Nutritional Sciences University Of Shizuoka
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Abe Naoki
Laboratory Of Applied Microbiology Department Of Microbial Biotechnology Graduate School Of Agricult
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