New Lignans from Kadsura coccinea and Their Nitric Oxide Inhibitory Activities
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概要
- 論文の詳細を見る
In vitro anti-allergic screening of medicinal herbal extracts revealed that the chloroform extract of the rhizoma of Kadsura coccinea inhibited nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage like cell line RAW 264.7. Further fractionation of the chloroform extract led to the isolation of three new lignans, including two dibenzocyclooctadiene lignans and one arylnaphthalene lignan, together with other three known dibenzocyclooctadiene lignans. This is the first report of NO production inhibitory activity of Kadsura coccinea and first report about the isolation of arylnaphthalene lignan from K. coccinea.
- 公益社団法人日本薬学会の論文
- 2006-07-01
著者
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XU Li-Zhen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical
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KITANAKA Susumu
College of Pharmacy, Nihon University
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Yang Shi-lin
National Pharmaceutical Engineering Centre For Solid Preparation In Chinese Herbal Medicine Jiangxi
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Yang Shi-lin
National Pharmaceutical Engineering Center For Solid Preparation In Chinese Herbal Medicine
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Xu Li-zhen
Inst. Of Medicinal Plant Dev. Chinese Acad. Of Medical Sciences & Peking Union Medical Coll.
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Xu Li-zhen
Institute Of Medicinal Plant Development Chinese Academy Of Medical Sciences And Peking Union Medica
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Kitanaka Susumu
Res. Unit Of Pharmacognosy School Of Pharmacy Nihon Univ.
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Kitanaka Susumu
College Of Pharmacy Nihon University
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WANG Jue
College of Pharmacy, Nihon University
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Wang Jue
College Of Pharmacy Nihon University
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LI He-Ran
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medic
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YANG Shi-Lin
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medic
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FENG Yu-Lin
Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical
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YANG Zhi-Gang
Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical
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DAIKONYA Akihiro
College of Pharmacy, Nihon University
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Yang Zhi-gang
China National Administration Center For Seabuckthorn Development Ministry Of Water Resources:colleg
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Daikonya Akihiro
Res. Unit Of Pharmacognosy School Of Pharmacy Nihon Univ.
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Daikonya Akihiro
College Of Pharmacy Nihon University
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Feng Yu-Lin
National Pharmaceutical Engineering Centre for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Traditional Chinese Medicine:Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical Colleg
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