Dynamics of Mitochondria during the Cell Cycle(Molecular and Cell Biology)
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概要
- 論文の詳細を見る
Mitochondria are highly dynamic organelles in eukaryotic cells. Although the role of mitochondria in metabolism, ATP production and apoptosis is more widely recognized, alterations in mitochondrial morphology and abundance are also important for cellular functions. Here we investigated mitochondrial dynamics in synchronized HeLa cells in which the major stages of the cell cycle of the observed cells were resolved by staining phosphorylate histones H1 and H3, and showed that mitochondria exist as filamentous network structures throughout the cell cycle progression, changing their morphology, distribution, and abundance. The current results suggest that mitochondrial condensation occurred at prophase is required for the proper progression of mitochondrial division.
- 公益社団法人日本薬学会の論文
- 2006-09-01
著者
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Shibata Hiroko
Laboratory Of Pharmaceutical Proteomics National Institute Of Biomedical Innovation (nibio)
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Shibata Hiroko
医薬基盤研究所 創薬プロテオミクスプロジェクト
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Shibata Hiroshi
Laboratory For Health Care Science Research Center Suntory Ltd.
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Shibata H
Laboratory For Health Care Science Research Center Suntory Ltd.
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SHIBATA Hirofumi
Department of Molecular Cell Biology and Medicine, Institute of Health Bioscience, The University of
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HIGUTI Tomihiko
Department of Molecular Cell Biology and Medicine, Institute of Health Bioscience, The University of
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ARAKAKI Naokatu
Department of Molecular Cell Biology and Medicine, Institute of Health Bioscience, The University of
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NISHIHAMA Takeshi
Department of Molecular Cell Biology and Medicine, Institute of Health Biosciences, The University o
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OWAKI Hiroyuki
Department of Molecular Cell Biology and Medicine, Institute of Health Biosciences, The University o
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KURAMOTO Yoshinori
Department of Molecular Cell Biology and Medicine, Institute of Health Biosciences, The University o
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SUENAGA Midori
Department of Molecular Cell Biology and Medicine, Institute of Health Biosciences, The University o
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MIYOSHI Eri
Department of Molecular Cell Biology and Medicine, Institute of Health Biosciences, The University o
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EMOTO Yuka
Department of Molecular Cell Biology and Medicine, Institute of Health Biosciences, The University o
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SHONO Masayuki
General Laboratory for Medical Research, Tokushima University School of Medicine, The University of
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Shono Masayuki
General Laboratory For Medical Research Tokushima University School Of Medicine The University Of To
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Shono Masayuki
General Lab. For Medical Research Tokushima Univ.
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Suenaga M
Pharmaceutical Research Division Takeda Chemical Industries Ltd.
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Himeda Toshiki
Faculty Of Pharmaceutical Science The University Of Tokushima
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Suenaga Midori
Department Of Molecular Cell Biology And Medicine Institute Of Health Biosciences The University Of
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Emoto Yuka
Department Of Molecular Cell Biology And Medicine Institute Of Health Biosciences The University Of
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Miyoshi Eri
Department Of Molecular Cell Biology And Medicine Institute Of Health Biosciences The University Of
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Owaki Hiroyuki
Department Of Molecular Cell Biology And Medicine Institute Of Health Biosciences The University Of
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Higuti T
Department Of Molecular Cell Biology And Medicine Institute Of Health Bioscience The University Of T
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Nishihama Takeshi
Department Of Molecular Cell Biology And Medicine Institute Of Health Biosciences The University Of
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Kuramoto Yoshinori
Department Of Molecular Cell Biology And Medicine Institute Of Health Biosciences The University Of
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Arakaki Naokatu
Department Of Molecular Cell Biology And Medicine Institute Of Health Bioscience The University Of T
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Saito Hiroyuki
Third Department Of Internal Medicine Asahikawa Medical College
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Shibata Hiroshi
Institute Of Health Care Science Suntory Wellness Limited
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ARAKAKI Naokatu
Department of Biochemistry, Kagoshima University Dental School(Present address): Department of Pharmaceutical Life Science, Faculty of Pharmaceutical Sciences, The University of Tokushima
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SHIBATA Hirofumi
Department of Microbial Chemistry, Faculty of Pharmaceutical Sciences, University of Tokushima
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Arakaki Naokatu
Department of Biochemistry, Kagoshima University Dental School
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