Hypoglycemic Action of Cyclocarya paliurus (Batal.) Iljinskaja in Normal and Diabetic Mice(Food & Nutrition Science)
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概要
- 論文の詳細を見る
This study examined the hypoglycaemic activity of Cyclocarya paliurus (Ratal.) Iljinskaja (C. paliurus) in ICR mice by oral glucose tolerance testing. The blood glucose level was significantly lower in the C. paliurus extract treatment group than in the control group after animals were given sucrose. This difference was not observed following the administration of glucose. We demonstrated that the chronological change in the level of blood glucose in genetically hyperglycemic obese KK-A^y mice is significantly lower when C. paliurus extract is administered daily for three weeks. An in vitro study showed that C. paliurus inhibits α-glucosidase, a disaccharide-degrading enzyme in the small intestinal mucosa, leading to a decrease in the absorption of glucose into the blood and a subsequent lowering of the blood glucose level.
- 社団法人日本農芸化学会の論文
- 2003-04-23
著者
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Shibata Hiroko
Laboratory Of Pharmaceutical Proteomics National Institute Of Biomedical Innovation (nibio)
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Shibata Hiroko
医薬基盤研究所 創薬プロテオミクスプロジェクト
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SHIBATA Hiroshi
Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd.
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Akimoto Kengo
Institute For Health Care Science Suntory Ltd.
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深見 治一
Institute For Biomedical Research Research Center Suntory Ltd.
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深見 治一
サントリー(株)基礎研
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KURIHARA Hiroshi
Institute of Traditional Chinese Medicine & Natural Products, Jinan University
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Tanaka Tetsuro
Laboratory Of Biopharmaceutics Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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Tanaka T
Institute For Health Care Science Suntory Ltd.
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Tanaka Takaharu
Institute For Health Care Science Suntory Ltd.
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Tanaka T
Suntory Consumer Health Products Division
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Shibata Hiroshi
Laboratory For Health Care Science Research Center Suntory Ltd.
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Kawanishi Hideaki
Institute For Health Care Science Suntory Ltd.
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Shibata H
Laboratory For Health Care Science Research Center Suntory Ltd.
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KUSUMOTO Aki
Institute for Health Care Science, Suntory Ltd.
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ASAMI Sumio
Institute for Health Care Science, Suntory Ltd.
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Fukami Harukazu
Institute for Health Care Science, Technological Development Center, Suntory Ltd.
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TOYODA Yoshiko
Institute for Health Care Science, Suntory Ltd.
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Toyoda Yoshiko
Institute For Health Care Science Suntory Ltd.
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Asami S
Institute For Health Care Science Suntory Ltd.
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Kusumoto Aki
Institute For Health Care Science Suntory Ltd.
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Fukami Harukazu
Department Of Bioscience And Biotechnology Faculty Of Bioenvironmental Science Kyotogakuen Universit
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Fukami Harukazu
Dep. Of Bioscience And Biotechnology Fac. Of Bioenvironmental Sci. Kyotogakuen Univ.
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Fukami Harukazu
Institute For Health Care Science Technological Development Center Suntory Ltd.
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Kurihara H
Institute Of Traditional Chinese Medicine And Natural Products Jinan University
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MATSUI Yokichi
Institute for Health Care Science, Suntory Ltd.
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Tanaka Takaharu
Institute For Fundamental Research Suntory Ltd.
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Fukami Harukazu
Department Of Bioscience And Biotechnology Faculty Of Bioenvironmental Science Kyotogakuen Universit
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Tanaka Takaharu
Institute For Biomedical Research Suntory Ltd.
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Matsui Yokichi
Institute For Health Care Science Suntory Ltd.
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Shibata Hiroshi
Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.:department Of Animal Scienc
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SHIBATA Hiroshi
Institute for Biomedical Research, Suntory Limited
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