Formal Total Synthesis of (-(-Indolmycin

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概要

• 論文の詳細を見る

• (+)-Indolmycenic ester 4,a key intermediate for the synthesis of (-)-indolmycin (1), was prepared from (2S, 3R)-epoxybutyrate 5 via (2S, 3S)-2-hydroxy-3-chlorobutyrate 6 or (2R, 3R)-2-mesyloxy-3-hydroxybutyrate 12,which were obtained by lipase-catalyzed kinefic resolution of the corresponding 2-acetates.

• 公益社団法人日本薬学会の論文
• 1990-02-25

著者

• 秋田 弘幸

  School of Pharmaceutical Sciences, Toho University

• 秋田 弘幸

  Riken Institute (The Institute of Physical and Chemical Research)

• 大石 武

  Riken Institute (The Institute of Physical and Chemical Research)

• 榎 裕子

  Riken Institute (The Institute of Physical and Chemical Research)

• 大石 武

  Faculty Of Engineering Yokohama National University:(present Address)meiji College Of Pharmacy

• 大石 武

  理研:(現)明治薬科大学

• 秋田 弘幸

  School Of Pharmaceutical Science Toho University

• 秋田 弘幸

  理化学研究所

• 川口 智子

  Riken Institute (the Institute Of Physical And Chemical Research)

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