The Use of Microorganisms in Oraganic Synthesis. V. Microbiological Asymmetric Reduction of Methyl 2-Methyl-3-(2-thienyl)-3-oxopropionate
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概要
- 論文の詳細を見る
Microbiological asymmetric reduction of methyl 2-methyl-3-(2-thienyl)-3-oxopropionate (3) by various yeasts was carried out. When Kloeckera saturnus was used, the C_3-(S)-alcohols 4c and 4d were obtained, whereas other yeasts such as Lipomyces starkeyi, Saccharomyces fermentati, and Sporobolomyces salmonicolor produced the isomeric C_3-(R)-alcohols 4a and 4b. On the other hand, when Endomycopsis fibligera, Hansenula anomala, and Candida albicans were used, the C_2-(S)-reduction products 4b and 4c were obtained.
- 公益社団法人日本薬学会の論文
- 1984-04-25
著者
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堀越 弘毅
Laboratory Of Bacteriology And Ecology The Institute Of Physical And Chemical Research (riken Instit
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秋田 弘幸
School Of Pharmaceutical Science Toho University
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秋田 弘幸
理化学研究所
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越地 弘子
Synthetic Organic Chemistry Laboratory The Institute Of Physical And Chemical Research (riken Instit
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古市 昭也
Synthetic Organic Chemistry Laboratory, The Institute of Physical and Chemical Research (Riken Insti
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秋田 弘幸
Synthetic Organic Chemistry Laboratory, The Institute of Physical and Chemical Research (Riken Insti
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大石 武
Laboratory of Bacteriology and Ecology, The Institute of Physical and Chemical Research (Riken Insti
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古市 昭也
Synthetic Organic Chemistry Laboratory The Institute Of Physical And Chemical Research (riken Instit
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