Reduction of Nitroolefin Using Microorganisms

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概要

• 論文の詳細を見る

• Microbial reduction of 1-phenyl-2-nitro-1-propen (3) was carried out using 57 stains of yeast, 40 strains of aerobic and facultatively anaerobic bacteria and 40 strains of strictly anaerobic bacteria. Nine strains of yeast (Candida tropicalis, etc., ) had the ability to reduce (3) to 1-phenyl-2-nitropropane (1)(94.1%-60.3% yield). The ability of the aerobic and anaerobic bacteria was weaker than yeast (35.6%-14.0% and less than 5%, respectively). When 11 straines of strictly anaerobic bacteria (Clostridium innocuum etc., ) were used, a final reduced product like amphetamine (2) was detected, although the efficiency of reduction was very poor.

• 公益社団法人日本薬学会の論文
• 1990-12-25

著者

• 秋田 弘幸

  School of Pharmaceutical Sciences, Toho University

• 秋田 弘幸

  Riken Institute (The Institute of Physical and Chemical Research)

• 大石 武

  Riken Institute (The Institute of Physical and Chemical Research)

• 大石 武

  Faculty Of Engineering Yokohama National University:(present Address)meiji College Of Pharmacy

• 大石 武

  理研:(現)明治薬科大学

• 秋田 弘幸

  School Of Pharmaceutical Science Toho University

• 秋田 弘幸

  理化学研究所

• 鈴木 邦夫

  理化学研究所動物・細胞システム研究室

• 森 啓

  Department of forensic Medicine, Faculty of Medicine, The University of Tokyo

• 石山 〓夫

  Department of forensic Medicine, Faculty of Medicine, The University of Tokyo

• 鈴木 邦夫

  Riken Institute

• 光岡 知足

  Riken Institute

• 森 啓

  Department Of Forensic Medicine Faculty Of Medicine The University Of Tokyo

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