The Reactions of Activated Amides. IV. The Reactions of Amide Acetals with Esters

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概要

• 論文の詳細を見る

• Attempted condensation of dimethylacetamide diethylacetal (Ia) with ethyl phenylacetate (IV) was unsuccessful whereas the reaction of N, N-dimethylvinylamine (IIa) with IV afforded crotonic acid derivative (V) (type A reaction). On the other hand, intramolecular condensation between amide acetals with ester carbonyl (type B reaction) was found to proceed smoothly. Thus, the enamino ketone derivatives (Xa, b) were obtained from the amide acetals (IXa, b) by simply refluxing them in t-butanol.

• 公益社団法人日本薬学会の論文
• 1969-11-25

著者

• 伴 義雄

  Faculty of Pharmaceutical Sciences, School of Medicine, Hokkaido University

• 大石 武

  Faculty Of Engineering Yokohama National University:(present Address)meiji College Of Pharmacy

• 伴 義雄

  東邦大・薬

• 伴 義雄

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 大石 武

  北大・薬:(現)理化学研究所

• 落合 美和子

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 中山 毎木

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 中山 毎木

  Faculty Of Pharmaceutical Sciences Hokkaido University

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