The Synthesis of 3-Spirooxindole Derivatives. I. Syntheses of 1-Methyl-2', 3', 10', 10'a-tetrahydrospiro [indoline-3,1' (5'H)-pyrrolo [1,2-b]-isoquinoline]-2-one and its Homologs.

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概要

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• The syntheses of 1-methyl-2', 3', 10', 10'a-tetrahydrospiro [indoline-3,1'(5'H)-pyrrolo-[1,2-b]isoquinoline]-2-one (XIII) and its homologs were described. The compound XIII was identified with the dehydrogenation product of 1-methyl-2-hydroxy-3-[2-(1,2,3,4-tetrahydro-2-isoquinolyl) ethyl] indole (XV), which established Belleau's assignment to the key intermediate in Julian's synthesis of the yohimbine ring system.

• 公益社団法人日本薬学会の論文
• 1963-04-25

著者

• 伴 義雄

  Faculty of Pharmaceutical Sciences, School of Medicine, Hokkaido University

• 大石 武

  Faculty Of Engineering Yokohama National University:(present Address)meiji College Of Pharmacy

• 伴 義雄

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 大石 武

  北大・薬:(現)理化学研究所

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